Epigenetics: differential DNA methylation in mammalian somatic tissues

H Nagase, S Ghosh - The FEBS journal, 2008 - Wiley Online Library
Epigenetics refers to heritable phenotypic alterations in the absence of DNA sequence
changes, and DNA methylation is one of the extensively studied epigenetic alterations. …

An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation

E Hannon, E Dempster, J Viana, J Burrage, AR Smith… - Genome biology, 2016 - Springer
differential DNA methylation associated with schizophrenia, we used a sliding window
approach (see Methods) [33], using permutations to establish an appropriate multiple testing …

Genomic Clustering of differential DNA methylated regions (epimutations) associated with the epigenetic transgenerational inheritance of disease and phenotypic …

MM Haque, EE Nilsson, LB Holder, MK Skinner - BMC genomics, 2016 - Springer
differential DNA methylation regions (DMRs) clusters are investigated in the current study. …
been extended in a recent analysis of DNA methylation data. A novel clustering approach …

Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia

SA Lee, KC Huang - BMC medical genomics, 2016 - Springer
… SDMGs, the epigenetic profiles of DNA differential methylation in schizophrenic postmortem
brain samples was analyzed in this study. Aberrant DNA methylation have been associated …

Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions

MK Skinner, C Guerrero-Bosagna - Bmc Genomics, 2014 - Springer
… Previously a variety of environmental toxicants were found to promote the epigenetic
transgenerational inheritance of disease through differential DNA methylation regions (DMRs), …

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

K Day, LL Waite, A Thalacker-Mercer, A West… - Genome biology, 2013 - Springer
epigenetic drift model is insufficient to explain all age-related changes in DNA methylation.
… Comparison of differential DNA methylation patterns between induced pluripotent stem cells …

Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure

M Movassagh, MK Choy, M Goddard, MR Bennett… - PloS one, 2010 - journals.plos.org
… Our results show that differential DNA methylation occurs in … differential DNA methylation
together with other epigenetic mechanisms such as histone de-acetylation. As these epigenetic

Differential DNA methylation between fetus and mother as a strategy for detecting fetal DNA in maternal plasma

LLM Poon, TN Leung, TK Lau, KCK Chow… - Clinical …, 2002 - academic.oup.com
epigenetic markers for the specific detection of fetal DNA in … We reasoned that, using DNA
methylation differences … limitations in the detection of fetal DNA in maternal plasma. For this …

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes

I Dahlman, I Sinha, H Gao, D Brodin, A Thorell… - International Journal of …, 2015 - nature.com
… explored DNA methylation and … differential gene expression in post-obese compared with
never-obese women. In contrast, adipogenesis genes displayed differential DNA methylation

Differential DNA methylation regions in adult human sperm following adolescent chemotherapy: potential for epigenetic inheritance

M Shnorhavorian, SM Schwartz, B Stansfeld… - PLoS …, 2017 - journals.plos.org
… correlations between the phenotypes and differential DNA methylation alterations in the sperm
[14]. … the epigenetic programming of the sperm and have the ability to promote epigenetic