Detection of significantly differentially methylated regions in targeted bisulfite sequencing data

K Hebestreit, M Dugas, HU Klein - Bioinformatics, 2013 - academic.oup.com
… pipeline to detect DNA methylation differences between cancer … DMRs by placing methylation
differences of various intensities … Differences d were sampled from a truncated Gamma: …

Regions of common inter-individual DNA methylation differences in human monocytes: genetic basis and potential function

C Schröder, E Leitão, S Wallner, G Schmitz… - Epigenetics & …, 2017 - Springer
… We modified BSmooth [13] to identify differentially methylated regions with a minimum
difference of 0.8 between the two synthetic methylomes. BSmooth is designed to …

Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites

A Kozlenkov, P Roussos, A Timashpolsky… - Nucleic acids …, 2014 - academic.oup.com
… regions harbor DNA methylation differences that distinguish … methylation differences relate
to cell-type–specific gene expression? We found that sites that are differentially methylated (…

A comparative analysis of DNA methylation across human embryonic stem cell lines

PY Chen, S Feng, JWJ Joo, SE Jacobsen, M Pellegrini - Genome biology, 2011 - Springer
… From BS-seq data we also identified CG sites that are differentially methylated between the
two … Interestingly, we observe significant differences in the global methylation levels between …

Identification of differentially methylated cell types in epigenome-wide association studies

SC Zheng, CE Breeze, S Beck, AE Teschendorff - Nature methods, 2018 - nature.com
differential methylation. We validated CellDMC on in silico mixtures of DNA methylation data
generated with different … the-art methods did not identify differential methylation. By applying …

Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors

S Lessard, M Beaudoin, K Benkirane, G Lettre - Genome medicine, 2015 - Springer
… We sought to identify differentially methylated single … differentially methylated CpGs are
hypermethylated in fetal erythroblasts. We can explore further these DNA methylation differences

A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta

AM Inkster, V Yuan, C Konwar, AM Matthews… - … of sex differences, 2021 - Springer
… analysis of sex differences in autosomal DNAme in the term … differentially methylated CpGs
and identify several key features of these loci that suggest their relevance to sex differences

[HTML][HTML] Genome-wide mapping of DNA methylation: a quantitative technology comparison

C Bock, EM Tomazou, A Brinkman, F Müller… - Nature …, 2010 - ncbi.nlm.nih.gov
… immunoprecipitation, MethylCap-seq: methylated DNA capture by affinity … accurate DNA
methylation data. However, these methods differ in their ability to detect differentially methylated

Longitudinal DNA methylation differences precede type 1 diabetes

RK Johnson, LA Vanderlinden, F Dong, PM Carry… - Scientific Reports, 2020 - nature.com
… The most statistically significant of 28 differentially methylated regions (DMRs) associated
… Our exploration of DNA methylation differences by natural history of the autoimmune phase …

ZNF718, HOXA4, and ZFP57 are differentially methylated in periodontitis in comparison with periodontal health: epigenome‐wide DNA methylation pilot study

HG Hernández… - Journal of …, 2021 - Wiley Online Library
… the differential counts into the statistical model used to determine DNA methylation differences
… Furthermore, there is evidence about the DNA methylation alterations in periodontitis are …