… However, when analyzing small numbers of samples with unique characteristics (eg normal
and affected tissue of a clinically unique patient or a manipulated cell model), large series of …

… the effect size is very small – such as, for example, where no differential probes with P<0.05 …
, gene associations and number of constituent CpGs per region are also reported. The user …

… Each targeted region typically includes a small number of … , ie small numbers of samples
relative to the number of … threshold, 0.05 divided by the number of CpG sites tested. This …

… number of software tools have been developed for identifying disease-associated differentially
methylated regions (… Differential methylation of a small subset (ie 500) of the clusters were …

… However, Bump Hunting is not sensitive to finding small DMRs involving a small number
of loci [46]. Similar to ICDMR, one of the previously mentioned methods, WFMM [36] also …

… a small number of aberrant DNA methylation profiles, ie 1–2% of RLGS spots [51]. Thus,
the DNA methylation … is a slightly aberrant DNA methylation status in a small number of T-DMRs. …

… to the differentially methylated regions in a format that is easily analyzed with limited … A
DMC approach is perhaps more useful when a small number of CpG sites are analyzed. …

… 0.2 and it outperformed the rest of methods when the methylation differences were especially
small (0.05). In addition, mCSEA returns a low number of FP, resulting in a high PPV for all …

… 2c), thus indicating that this genomic region has a low level of methylation. On the other … )
due to their smaller size (Fig. 4). The overall large quantity of differential methylation found by …

… compared at the same number of false-positive mC calls (Figure 2a). The difference in
true-positive rates was especially remarkable when only a small number of false positives were …