… epigenetic changes characteristic of disease provide a unique … of DNA methylation changes
that result or lead to disease, … the detection and analysis of DNA methylation and provide a …

… As any testing for detection and diagnosis should preferably … DNA methylation analysis for
the detection and diagnosis of … of DNA methylation patterns may help with disease diagnosis…

… validate disease-specific DNA methylation changes as a diagnostic biomarker. Here, we
highlight the advantages of DNA methylation signature for diagnosis in different diseases and …

… disease subtype, aggressiveness, and treatment response. DNA methylation-based molecular
diagnostic … analyte (DNA) and the potential sensitivity of the assays. As the field matures, …

… findings on DNA methylation in these common human diseases using autoimmune diseases,
… In addition, the level of DNA methylation at diagnosis is associated with the response to …

… DNA methylation as a biomarker, the practical considerations for their development, and their
use in disease … also to evoke their potential for complex diseases and prenatal diagnostics. …

… status of specific genes but rather on the concept of DNA methylation patterns as …
article we refer to DNA methylation as methylation. ANALYSIS OF METHYLATION STATUS …

… might still be a useful biomarker for tumor diagnosis or risk assessment if the methylation
pattern is specific for a certain tumor type and/or correlates with clinically important parameters. …

… As with disease phenotypes, each clinical DNA methylation biomarker would need to be …
identifying diagnostic DNA methylation biomarkers suitable for early detection and diagnosis of …

… usually disturbs signal pathways and contributes to the development of several diseases,
and it was the first epigenetic changes to be identified in tumor [50]. Abnormal …