DNA methylation in mammalian development and disease

W Dean, D Lucifero, F Santos - Birth Defects Research Part C …, 2005 - Wiley Online Library
… Together, these results suggest a mutual interrelatedness of the MTases to create and
maintain distinctive patterns and levels of DNA methylation that define specific genomic regions. …

DNA methylation contributes to natural human variation

H Heyn, S Moran, I Hernando-Herraez… - Genome …, 2013 - genome.cshlp.org
DNA methylation patterns are important for establishing cell, tissue, and organism … into
the potential impact of DNA methylation changes on distinct human phenotypes beyond the …

Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns

Y Zhou, S Liu, Y Hu, L Fang, Y Gao, H Xia… - BMC biology, 2020 - Springer
… assembly markedly improved DNA methylation results. We … methylation patterns of global
CpG sites, partially methylated … a distinct set of PMDs, which showed tissue-specific patterns. …

Blood-based DNA methylation in advanced Nasopharyngeal Carcinoma exhibited distinct CpG methylation signature

K Chatterjee, S Mal, M Ghosh, NR Chattopadhyay… - Scientific Reports, 2023 - nature.com
methylation in advanced NPC. Therefore, we aimed to determine the DNA methylation signature
from … in DNA methylation patterns of blood and tissue of NPC patients to identify unique …

Eukaryotic DNA methylation as an evolutionary device

V Colot, JL Rossignol - Bioessays, 1999 - Wiley Online Library
… at least five structurally distinct subfamilies. Furthermore, it is now clear that DNA methylation
can be … The genomewide pattern is a distinctive feature of mammals and other vertebrates …

Heterogeneity and randomness of DNA methylation patterns in human embryonic stem cells

AG Tsai, DM Chen, M Lin, JCF Hsieh… - DNA and cell …, 2012 - liebertpub.com
… Whether a distinct and nonrandom DNA methylation pattern is present at a … DNA methylation
patterns are much less apparent because the data are often obtained only as methylation

Chromatin modifications and genomic contexts linked to dynamic DNA methylation patterns across human cell types

H Yan, D Zhang, H Liu, Y Wei, J Lv, F Wang, C Zhang… - Scientific reports, 2015 - nature.com
DNA methylation patterns in different genomic regions, the whole genome-wide DNA methylation
patterns … In this study, however, distinct correlations were observed between sequence …

Inflammation-associated DNA methylation patterns in epithelium of ulcerative colitis

A Barnicle, C Seoighe, JM Greally, A Golden… - Epigenetics, 2017 - Taylor & Francis
… This epigenomic study has reported distinct patterns of DNA methylation and gene
expression in the inflamed epithelial cells of UC. These results have shown that differential …

Expression of myeloperoxidase in acute myeloid leukemia blasts mirrors the distinct DNA methylation pattern involving the downregulation of DNA methyltransferase …

H Itonaga, D Imanishi, YF Wong, S Sato, K Ando… - Leukemia, 2014 - nature.com
… significantly related to a specific DNA methylation pattern affecting MPO gene transcription
in … that the methylation pattern of the 33 genes, determined by a DNA methylation microarray, …

DNA methylation profiles of differentiated‐type gastric carcinomas with distinct mucin phenotypes

J Motoshita, N Oue, H Nakayama, K Kuraoka… - Cancer …, 2005 - Wiley Online Library
… be involved partly in the distinct phenotypic expression of GC… Distinct genetic changes
appear to be associated with I type … suggest that changes in DNA methylation patterns, such as …