Impaired active demethylation of the paternal genome in pronuclear‐stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection
Y Yoshizawa, M Kato, M Hirabayashi… - Molecular …, 2010 - Wiley Online Library
… rat embryo production (IVF and ICSI) influenced the extent, but not the timing, of active
demethylation … Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol …
demethylation … Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol …
Demethylation in early embryonic development and memory
C Bernstein, H Bernstein - DNA Methylation Mechanism, 2019 - books.google.com
… At 24 h after training, 9.2% of the genes in the rat genomes of hippocampus neurons are …
embryonic development in evolution depended on preexisting DNA methylation/demethylation …
embryonic development in evolution depended on preexisting DNA methylation/demethylation …
Demethylation of CpG islands in embryonic cells
D Frank, I Keshet, M Shani, A Levine, A Razin, H Cedar - Nature, 1991 - nature.com
… and de novo methylation. To test whether DNA methylation inhibits gene expression in vivo,
… , b, Plasmid plns-1 containing the complete rat insulin-1 gene" was methylated in vitro with …
… , b, Plasmid plns-1 containing the complete rat insulin-1 gene" was methylated in vitro with …
Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes
… DNA demethylation in cloned embryos at 2–8 h post‐activation (hpa). Ab's against 5mC show
a strong IF signal in activated SCNT embryos … Line1/ETn methylation in cloned embryos. (A…
a strong IF signal in activated SCNT embryos … Line1/ETn methylation in cloned embryos. (A…
Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes
JS Park, YS Jeong, ST Shin, KK Lee… - … dynamics: an official …, 2007 - Wiley Online Library
… DNA methylation patterns can be globally reset at certain developmental stages: first in
primordial germ cells and then in preimplantation embryos … actively demethylated (mouse and rat)…
primordial germ cells and then in preimplantation embryos … actively demethylated (mouse and rat)…
[HTML][HTML] Vitamin C Rescues in vitro Embryonic Development by Correcting Impaired Active DNA Demethylation
M Chu, F Yao, G Xi, J Yang, Z Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
… DNA demethylation in IVF embryos, we next asked if the gene expression level of Tet family
members was inhibited in IVF preimplantation embryos. … inhibited in IVF embryos at the two- …
members was inhibited in IVF preimplantation embryos. … inhibited in IVF embryos at the two- …
Active DNA demethylation of the vertebrate genomes by DNA methyltransferases: deaminase, dehydroxymethylase or demethylase?
KY Wang, CC Chen, CKJ Shen - Epigenomics, 2014 - Future Medicine
… that the DNA demethylation and dehydroxymethylation activities of the vertebrate DNMTs
play essential roles in multiple biological processes including early embryo development, …
play essential roles in multiple biological processes including early embryo development, …
Non-coding RNA directed DNA demethylation of Sphk1 CpG island
… (D) In situ hybridization of Khps1 in cultured cells prepared from rat fetuses. An FITC-conjugated
anti-digoxigenin antibody (green) was reacted to visualize the probe complementary to …
anti-digoxigenin antibody (green) was reacted to visualize the probe complementary to …
DNA demethylation by DNA repair
… Imprinting takes place in the endosperm, a tissue that supports embryo growth during seed
development and seedling germination. Active DNA demethylation has been implicated in …
development and seedling germination. Active DNA demethylation has been implicated in …
[HTML][HTML] Dynamic changes in DNA modification states during late gestation male germ line development in the rat
CM Rose, S Van Den Driesche, RM Sharpe… - Epigenetics & …, 2014 - Springer
… Mouse studies indicate that DNA demethylation may be initiated at embryonic day (e) 8
and … of DNA methylation in the fetal rat testis for all currently recognised forms of cytosine …
and … of DNA methylation in the fetal rat testis for all currently recognised forms of cytosine …