… We hypothesized that since copper deficiency by itself can be harmful to the developing
embryo and fetus and that it contributes to oxidative stress and/or hypoxia produced by diabetes …

… methylation/demethylation pattern of both pronuclei in human zygotes and in early embryos
up … In general, our results show that, as in other mammals tested so far (mouse, pig, rat and …

… on global DNA methylation and the methylation status at … DNA methylation status of
spermatozoa was evaluated at the global and at the Igf2-H19 ICR locus, and the DNA methylation …

… DNA methylation patterns are established through epigenetic reprogramming. However,
established DNA methylation … the elder rat liver, folate supplementation increases genomic DNA …

… to regulate DNA demethylation within a key enhancer of the rat … receptor uses local DNA
demethylation as one of several … culture of hepatocytes isolated from ed15 fetuses, ie before the …

… embryonic stem cells (ESCs) in serum, to lineage-primed epiblast stem cells (EpiSCs). To
investigate the role of DNA methylation (5mC) … and global DNA demethylation. Mechanistically, …

… (D) In situ hybridization of Khps1 in cultured cells prepared from rat fetuses. An FITC-conjugated
anti-digoxigenin antibody (green) was reacted to visualize the probe complementary to …

… DNA methylation in eucaryotes, we have analyzed the 5-methylcytosine content of DNA for
different cell populations of embryonic … 5-methylcytosine content of rat brain DNA must be due …

… in vitro developed embryos are easily available, the status of DNA methylation levels in both
… has been reported in cattle7 and rats.However, in other species, such as pigs and goats, …

… during embryo development. On the contrary, there are hints that the DNA methylation status
… Studying rat myoblasts, Weiss et al66 proposed that demethylation takes place through the …