… Our results demonstrate that defects in DNA maintenance methylation in the embryo, not
in the mother, are associated with abnormal embryonic implantation and development. The …

… global DNA demethylation, which is vital for the totipotency of the developing embryo. Hackett
… rare regulatory elements that escape systematic DNA demethylation in PGCs, providing a …

… at specific regions may be controlled by activation of DNA methylation transferases (DNMT).DNA …
stimuli, including diet, may increase hepatic DNA methylation in either fetus or …

… embryo culture, Liu and colleagues (2009b) showed that there was increased DNA methylation
… induced effect on the methylation was a function of whether the embryo showed a neural …

… embryos. However, smaller amounts of UHRF1 existed in the nucleus, consistent with the
expected role in DNA methylation. We … , a large proportion of the embryos derived from the KO …

… resulted in alterations in fertilization and early embryo development. We suggest that 5-azacytidine-induced
alterations in germ cell DNA methylation patterns may be one of the under…

… Aberrant DNA methylation during embryo formation in … lethality and growth abnormalities in
surviving embryos [Kang et al., … cell line are mirrored in the rat, late in embryogenesis and at …

… in the DNA methylation machinery, namely, de novo DNA … of proteins involved in DNA
methylation-mediated gene … of the alteration in the DNA methylation machinery at early stages of …

… To study the influence of gene methylation in the Shh/Bmp4 signaling pathway on the
enteric nervous system in the rectum of rat embryos with anorectal malformations (ARMs). …

… Comparable levels of DNA methylation were found in IV embryos and in … In conclusion, DNA
methylation patterns were adversely … of DNA-demethylation in early mouse and rat embryos …