Epigenetic mechanisms of DNA methylation in the transgenerational effect of ethylhexyl salicylate on zebrafish

R Zhou, G Lu, Z Yan, R Jiang, Y Sun, P Zhang - Chemosphere, 2022 - Elsevier
… and offsprings; 2) EHS may induce transgenerational toxicity by inducing abnormal DNA
methylation levels, DNA methylation modification sites and DNA methylation regulatory enzyme …

… of hot spots of DNA methylation in the adult male adrenal in response to in utero exposure to the ubiquitous endocrine disruptor plasticizer di-(2-ethylhexyl) phthalate

DB Martinez-Arguelles, V Papadopoulos - Endocrinology, 2015 - academic.oup.com
… Under the same experimental conditions, we used reduced-representation bisulfite
sequencing to assess changes in DNA methylation. We identified hot spots of DNA methylation

Global DNA methylation mediates the association between urine mono-2-ethylhexyl phthalate and serum apoptotic microparticles in a young Taiwanese population

CY Lin, CW Chen, HL Lee, C Wu, C Wang… - Science of The Total …, 2022 - Elsevier
… levels of mono-2-ethylhexyl phthalate (MEHP) … DNA methylation mediates the relationship
between MEHP and apoptotic microparticles. These findings indicate that DNA methylation

Reproductive effects linked to DNA methylation in male zebrafish chronically exposed to environmentally relevant concentrations of di-(2-ethylhexyl) phthalate

YB Ma, PP Jia, M Junaid, L Yang, CJ Lu, DS Pei - Environmental Pollution, 2018 - Elsevier
… The DNA methylation statuses of these genes were altered within their promoter regions.
A significant increase in global DNA methylation in both the male testes and their offspring …

The association between urine di-(2-ethylhexyl) phthalate metabolites, global DNA methylation, and subclinical atherosclerosis in a young Taiwanese population

CY Lin, HL Lee, YT Hwang, C Wang, CJ Hsieh… - Environmental …, 2020 - Elsevier
… , including DNA methylation, in CVD. Moreover, DEHP exposure has proved to alter DNA
methylation in … However, the interplay between DEHP exposure, global DNA methylation, and …

Prenatal and ancestral exposure to di (2-ethylhexyl) phthalate alters gene expression and DNA methylation in mouse ovaries

S Rattan, HK Beers, A Kannan, A Ramakrishnan… - Toxicology and applied …, 2019 - Elsevier
… cycle regulators, apoptosis factors, Esr2, DNA methylation mediators, and the percentage of
5… gene expression may be influenced by DNA methylation. These results provide insight into …

… DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono (2-ethylhexyl) …

JH Kamstra, LB Sales, P Aleström, J Legler - Epigenetics & chromatin, 2017 - Springer
… Our results suggest a functional role for DNA methylation on cis-regulatory conserved
elements following developmental exposure to compounds. Effects on these regions are …

Effect of Mono-2-ethyhexyl phthalate on DNA methylation in human prostate cancer LNCaP cells

JH Wu, C Jiao, W Yong, XIA Bin, W Rong, Z Yan… - Biomedical and …, 2017 - Elsevier
… exposed to di (2-ethylhexyl) phthalate [also known as Bis (2-ethylhexyl) benzene-1, … can
affect DNA methylation in LNCaP cells, as well as the potential role of DNA methylation in the …

… sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di (2ethylhexyl) phthalate (DEHP) is associated with DNA methylation …

CK Chou, HW Huang, CF Yang… - Environmental …, 2019 - Wiley Online Library
… Genome‐wide DNA methylation profiling revealed that after 48 hours of exposure to 100
μM DEHP, MCF‐7 cells exhibited a significant change in their DNA methylation pattern, …

Bis (2-ethylhexyl)-2, 3, 4, 5-tetrabromophthalate affects lipid metabolism in zebrafish larvae via DNA methylation modification

W Guo, J Han, S Wu, X Shi, Q Wang… - … Science & Technology, 2019 - ACS Publications
… in the DNA methylation ratios of the … 2B); likewise, a significant decrease in the DNA
methylation ratio is observed for the 20, 200, and 2000 nM TBMEHP treatment groups (Figure 2B). …