Epigenetic mechanisms of DNA methylation in the transgenerational effect of ethylhexyl salicylate on zebrafish
R Zhou, G Lu, Z Yan, R Jiang, Y Sun, P Zhang - Chemosphere, 2022 - Elsevier
… and offsprings; 2) EHS may induce transgenerational toxicity by inducing abnormal DNA
methylation levels, DNA methylation modification sites and DNA methylation regulatory enzyme …
methylation levels, DNA methylation modification sites and DNA methylation regulatory enzyme …
… of hot spots of DNA methylation in the adult male adrenal in response to in utero exposure to the ubiquitous endocrine disruptor plasticizer di-(2-ethylhexyl) phthalate
DB Martinez-Arguelles, V Papadopoulos - Endocrinology, 2015 - academic.oup.com
… Under the same experimental conditions, we used reduced-representation bisulfite
sequencing to assess changes in DNA methylation. We identified hot spots of DNA methylation …
sequencing to assess changes in DNA methylation. We identified hot spots of DNA methylation …
Global DNA methylation mediates the association between urine mono-2-ethylhexyl phthalate and serum apoptotic microparticles in a young Taiwanese population
CY Lin, CW Chen, HL Lee, C Wu, C Wang… - Science of The Total …, 2022 - Elsevier
… levels of mono-2-ethylhexyl phthalate (MEHP) … DNA methylation mediates the relationship
between MEHP and apoptotic microparticles. These findings indicate that DNA methylation …
between MEHP and apoptotic microparticles. These findings indicate that DNA methylation …
Reproductive effects linked to DNA methylation in male zebrafish chronically exposed to environmentally relevant concentrations of di-(2-ethylhexyl) phthalate
YB Ma, PP Jia, M Junaid, L Yang, CJ Lu, DS Pei - Environmental Pollution, 2018 - Elsevier
… The DNA methylation statuses of these genes were altered within their promoter regions.
A significant increase in global DNA methylation in both the male testes and their offspring …
A significant increase in global DNA methylation in both the male testes and their offspring …
The association between urine di-(2-ethylhexyl) phthalate metabolites, global DNA methylation, and subclinical atherosclerosis in a young Taiwanese population
CY Lin, HL Lee, YT Hwang, C Wang, CJ Hsieh… - Environmental …, 2020 - Elsevier
… , including DNA methylation, in CVD. Moreover, DEHP exposure has proved to alter DNA
methylation in … However, the interplay between DEHP exposure, global DNA methylation, and …
methylation in … However, the interplay between DEHP exposure, global DNA methylation, and …
Prenatal and ancestral exposure to di (2-ethylhexyl) phthalate alters gene expression and DNA methylation in mouse ovaries
S Rattan, HK Beers, A Kannan, A Ramakrishnan… - Toxicology and applied …, 2019 - Elsevier
… cycle regulators, apoptosis factors, Esr2, DNA methylation mediators, and the percentage of
5… gene expression may be influenced by DNA methylation. These results provide insight into …
5… gene expression may be influenced by DNA methylation. These results provide insight into …
… DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono (2-ethylhexyl) …
… Our results suggest a functional role for DNA methylation on cis-regulatory conserved
elements following developmental exposure to compounds. Effects on these regions are …
elements following developmental exposure to compounds. Effects on these regions are …
Effect of Mono-2-ethyhexyl phthalate on DNA methylation in human prostate cancer LNCaP cells
JH Wu, C Jiao, W Yong, XIA Bin, W Rong, Z Yan… - Biomedical and …, 2017 - Elsevier
… exposed to di (2-ethylhexyl) phthalate [also known as Bis (2-ethylhexyl) benzene-1, … can
affect DNA methylation in LNCaP cells, as well as the potential role of DNA methylation in the …
affect DNA methylation in LNCaP cells, as well as the potential role of DNA methylation in the …
… sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di (2‐ethylhexyl) phthalate (DEHP) is associated with DNA methylation …
CK Chou, HW Huang, CF Yang… - Environmental …, 2019 - Wiley Online Library
… Genome‐wide DNA methylation profiling revealed that after 48 hours of exposure to 100
μM DEHP, MCF‐7 cells exhibited a significant change in their DNA methylation pattern, …
μM DEHP, MCF‐7 cells exhibited a significant change in their DNA methylation pattern, …
Bis (2-ethylhexyl)-2, 3, 4, 5-tetrabromophthalate affects lipid metabolism in zebrafish larvae via DNA methylation modification
… in the DNA methylation ratios of the … 2B); likewise, a significant decrease in the DNA
methylation ratio is observed for the 20, 200, and 2000 nM TBMEHP treatment groups (Figure 2B). …
methylation ratio is observed for the 20, 200, and 2000 nM TBMEHP treatment groups (Figure 2B). …
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