Whole-genome DNA methylation analyses revealed epigenetic instability in tumorigenic human iPS cell-derived neural stem/progenitor cells

T Iida, A Iwanami, T Sanosaka, J Kohyama… - Stem …, 2017 - academic.oup.com
… The results of this analysis revealed that most regions within the CAT TSS500 were
hypermethylated in 253G1-NS/PCs and were demethylated in 201B7-NS/PCs. Moreover, a …

Combined bioinformatics analysis reveals gene expression and DNA methylation patterns in osteoarthritis

D Song, W Qi, M Lv, C Yuan… - Molecular Medicine …, 2018 - spandidos-publications.com
… The results of the present study revealed that the majority of DEGs and DMSs were …
Cross analysis revealed 30 genes that exhibited differential expression and methylation in …

DNA methylation analysis identifies loci for blood pressure regulation

MA Richard, T Huan, S Ligthart, R Gondalia… - The American Journal of …, 2017 - cell.com
methylation, gene expression, and BP. Additional integrative Mendelian randomization
analyses of gene expression and DNA methylation … of association between DNA methylation at …

Longitudinal genome-wide DNA methylation analysis uncovers persistent early-life DNA methylation changes

RF Pérez, P Santamarina, JR Tejedor… - Journal of translational …, 2019 - Springer
… However, our analysis revealed persistent DNA methylation changes at 240 CpG sites,
indicating that there are genomic locations of considerable epigenetic change beyond immediate …

Genome‐wide allelic methylation analysis reveals disease‐specific susceptibility to multiple methylation defects in imprinting syndromes

F Court, A Martin‐Trujillo, V Romanelli, I Garin… - Human …, 2013 - Wiley Online Library
Genomic imprinting is the parent‐of‐origin‐specific allelic transcriptional silencing observed
in mammals, which is governed by DNA methylation established in the gametes and …

Comprehensive DNA methylation and mutation analyses reveal a methylation signature in colorectal sessile serrated adenomas

ÁV Patai, BK Barták, B Péterfia, T Micsik… - Pathology & Oncology …, 2017 - Springer
… microsatellite instable by immunohistochemical analysis. Our combined mutation and DNA
methylation analysis revealed that there is a common DNA methylation signature present in …

[HTML][HTML] Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic …

JG Kim, H Takeshima, T Niwa, E Rehnberg… - Cancer letters, 2013 - Elsevier
… In this study, we conducted comprehensive DNA methylation analysis and extensive mutation
analysis of 30 GCs, and showed (1) that the number of aberrantly methylated genes was …

Integrated epigenomics analysis reveals a DNA methylation panel for endometrial cancer detection using cervical scrapings

RL Huang, PH Su, YP Liao, TI Wu, YT Hsu, WY Lin… - Clinical Cancer …, 2017 - AACR
DNA methylation is a promising cancer biomarker, but limited use for detecting endometrial
… the methylation pattern and reduced the candidate genes. We verified in pools DNA from …

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

E Hannon, EL Dempster, G Mansell, J Burrage, N Bass… - Elife, 2021 - elifesciences.org
We performed a systematic analysis of blood DNA methylation profiles from 4483
participants from seven independent cohorts identifying differentially methylated positions (DMPs) …

Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects

KR van Eijk, S de Jong, MPM Boks, T Langeveld… - BMC genomics, 2012 - Springer
… correlation network analysis revealed that i) both transcriptome and methylome are organized
in modules, ii) co-expression modules are generally not preserved in the methylation data …