[HTML][HTML] DNA methylation and demethylation in mammals

Z Chen, AD Riggs - Journal of Biological Chemistry, 2011 - ASBMB
… , a wave of global de novo methylation re-establishes the DNA methylation patterns that will
be maintained, in large part, in somatic tissues. Genome-wide demethylation also occurs in …

Mechanisms of DNA methylation and demethylation in mammals

G Auclair, M Weber - Biochimie, 2012 - Elsevier
… of DNA methylation are highly dynamic between cell types. Here, we discuss the importance
of DNA methylation for genome regulation and the mechanisms that remodel the DNA

[HTML][HTML] DNA methylation and its basic function

LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
DNA methylation and demethylation. As a consequence, differentiated cells develop a stable
and unique DNA methylation … the process of DNA methylation and demethylation in the …

DNA demethylation

AP Wolffe, PL Jones, PA Wade - Proceedings of the …, 1999 - National Acad Sciences
… Understanding the biochemistry of DNA methylation dynamics is a problem of tremendous …
molecular mechanisms that target both DNA methylation and demethylation is essential. Such …

DNA methylation and demethylation: a pathway to gametogenesis and development

W Dean - Molecular Reproduction and Development, 2014 - Wiley Online Library
… addition and subtraction of DNA methylation and its oxidative products, coupled to the
mechanisms at play to achieve this goal. The activities competent to add DNA methylation, and …

DNA methylation and demethylation as targets for anticancer therapy

M Szyf - Biochemistry (Moscow), 2005 - Springer
… of DNA methylation were shown to activate methylated tumor suppressor genes and inhibit
tumor growth, demethylation of … This review discusses the emerging role of demethylation in …

DNA methylation and demethylation in plant immunity

A Deleris, T Halter, L Navarro - Annual review of phytopathology, 2016 - annualreviews.org
… Here, we focus on DNA methylation, which refers to the … biological relevance of DNA
methylation, as well as demethylation, in … Furthermore, we present the dynamics of DNA

Target specificity of mammalian DNA methylation and demethylation machinery

M Ravichandran, RZ Jurkowska… - Organic & biomolecular …, 2018 - pubs.rsc.org
… maintenance of the methylation pattern, both generation of DNA methylation and its removal
… of ongoing DNA methylation and demethylation shapes the final epigenetic methylation

Methylation and demethylation in the regulation of genes, cells, and responses in the immune system

DR Fitzpatrick, CB Wilson - Clinical immunology, 2003 - Elsevier
DNA methylation is a focus of epigenetic research in the immune system. This overview
begins with a synopsis of the players and processes involved in DNA methylation, demethylation

DNA methylation and demethylation probed by small molecules

M Szyf - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2010 - Elsevier
… of the DNA demethylating activity is still a mystery, the development of DNA demethylation
inhibitors … This review will discuss DNA methylation and demethylation machineries, and their …