… , a wave of global de novo methylation re-establishes the DNA methylation patterns that will
be maintained, in large part, in somatic tissues. Genome-wide demethylation also occurs in …

… of DNA methylation are highly dynamic between cell types. Here, we discuss the importance
of DNA methylation for genome regulation and the mechanisms that remodel the DNA …

… DNA methylation and demethylation. As a consequence, differentiated cells develop a stable
and unique DNA methylation … the process of DNA methylation and demethylation in the …

… Understanding the biochemistry of DNA methylation dynamics is a problem of tremendous …
molecular mechanisms that target both DNA methylation and demethylation is essential. Such …

… of DNA methylation were shown to activate methylated tumor suppressor genes and inhibit
tumor growth, demethylation of … This review discusses the emerging role of demethylation in …

… addition and subtraction of DNA methylation and its oxidative products, coupled to the
mechanisms at play to achieve this goal. The activities competent to add DNA methylation, and …

… Here, we focus on DNA methylation, which refers to the … biological relevance of DNA
methylation, as well as demethylation, in … Furthermore, we present the dynamics of DNA …

… First, we provide a brief background on how methylation status is empirically … of DNA
methylation with chromatin. Finally, we consider possible regulatory roles of DNA methylation in …

… maintenance of the methylation pattern, both generation of DNA methylation and its removal
… of ongoing DNA methylation and demethylation shapes the final epigenetic methylation …

… of the DNA demethylating activity is still a mystery, the development of DNA demethylation
inhibitors … This review will discuss DNA methylation and demethylation machineries, and their …