Functions of DNA methylation and hydroxymethylation in mammalian development

S Guibert, M Weber - Current topics in developmental biology, 2013 - Elsevier
… methylates hemimethylated sites generated after DNA replication. Lack of maintenance
methylation results in passive loss of DNA methylation with DNA replication. TET proteins are …

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… More recently, attention has been given to DNA hydroxymethylation (5-… pathways for treating
AD through correcting methylation and hydroxymethylation alterations. In the present study, …

DNA methylation and hydroxymethylation in stem cells

Y Cheng, N Xie, P Jin, T Wang - Cell biochemistry and function, 2015 - Wiley Online Library
DNA methylation patterns are essential for successful nuclear reprogramming. In the past
several years, the rediscovery of hydroxymethylationDNA methylation and hydroxymethylation

DNA methylation and hydroxymethylation in hematologic differentiation and transformation

M Ko, J An, A Rao - Current opinion in cell biology, 2015 - Elsevier
… demethylation, these oxidized methylcytosines are novel epigenetic modifications of DNA.
DNA methylation and hydroxymethylation profiles are markedly disrupted in a wide range of …

Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage

M Kim, YK Park, TW Kang, SH Lee… - Human molecular …, 2014 - academic.oup.com
DNA methylation and hydroxymethylation have been implicated in normal development and
differentiation, but our knowledge is limited about the genome-wide distribution of 5-…

Quantifying propagation of DNA methylation and hydroxymethylation with iDEMS

KR Stewart-Morgan, CE Requena, V Flury, Q Du… - Nature Cell …, 2023 - nature.com
… In euchromatin, DNA methylation is found in active gene bodies, … DNA methylation can be
oxidized to hydroxymethylation (… Loss of DNA methylation causes genome instability that can …

DNA methylation and hydroxymethylation in cancer

F Asmar, A Søgaard, K Grønbæk - Epigenetic Cancer Therapy, 2015 - Elsevier
DNA methylation and hydroxymethylation patterns in cancer, mutations in epigenetic regulators
involved in DNA methylation … aberrant DNA methylation and hydroxymethylation patterns …

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

AR Smith, RG Smith, E Pishva, E Hannon… - Clinical …, 2019 - Springer
… association study of both DNA methylation and hydroxymethylation in Alzheimer’s disease
entorhinal cortex. We demonstrate that previous estimates of DNA hypermethylation in ANK1 …

[HTML][HTML] Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

L Chouliaras, D Mastroeni, E Delvaux, A Grover… - Neurobiology of …, 2013 - Elsevier
… that DNA methylation and DNA hydroxymethylation are 2 … of markers of DNA methylation
and hydroxymethylation in the … markers of DNA methylation and hydroxymethylation, that is, 5-…

Comprehensive DNA methylation and hydroxymethylation analysis in the human brain and its implication in mental disorders

T Kato, K Iwamoto - Neuropharmacology, 2014 - Elsevier
… of DNA methylation and hydroxymethylation. In this review, recent studies on the comprehensive
analysis of DNA methylation and hydroxymethylation … the roles for methylation in mental …