… In summary, chromatin modification and DNA methylation and demethylation machineries …
in DNA methylation or histone modification require targeting of histone and DNA modification …

… Understanding the molecular determinants of both normal and abnormal patterns of chromatin
formation and DNA methylation thus holds great promise for our understanding of cancer …

… Collectively, proteins associated with chromatin affect establishment of DNA methylation
pattern directly or indirectly via histone modifications, and inversely, DNA methylation influ…

… Our studies thus suggest that the average residence time of H1 on chromatin is not substantially
affected by DNA methylation itself or its derivative histone modification pattern. Rather, it …

… closed chromatin structure owing to de novo methylation that … the maintenance of DNA
methylation and chromatin structure … in chromatin structure and removal of DNA methylation 55 . …

… modifications of the mammalian genome. A model will also be put forth to account for how
chromatin modifications lead to genomic DNA methylation … DNA methylation is an epigenetic …

… that epigenetics is achieved by DNA methylation and chromatin. Wolffe further placed …
DNA methyltransferases, methyl-CpG binding proteins, histone-modifying enzymes, chromatin …

… methylated regions are typical of the bulk chromatin … methylation also prevents activation
by blocking the access of transcription factors.63,66 Whether this chromatin effect of methylation …

… co-repressors, chromatin remodeling proteins and histone … DNA methylation could then
target the formation of chromatin… of chromatin formation suggest that DNA methylation and …

… between DNA methylation and chromatin … chromatin states may dictate genome-wide DNA
methylation patterning. The mammalian DNA methylation machinery – properties of the DNA …