… of ageing based on DNA methylation data have enabled accurate age estimates for any
tissue across the entire life course. These ‘epigenetic clocks’ link developmental and …

… collections of individual methylation sites whose aggregate methylation status measures
chronological age, referred to as the DNA methylation clock. DNA methylation may also have …

… fascinating discovery of “DNA methylation clocks” has brought … and current state of the clocks
themselves; we refer readers to … Here, we define a “DNA methylation clock” as an estimator …

… in DNA methylation level patterns and aging. In addition, we introduce the known mechanisms
by which DNA methylation … the mechanisms by which DNA methylation regulates aging, …

… , which are based on the concept that DNA methylation status is … Herein we describe the utility
of DNA methylation clocks as … A proper understanding of DNA methylation clocks, as aging …

… Hence, evaluating several DNAm clocks together may be the most effective strategy in …
DNAm clock predictions. In the current review, we discuss 15 reported DNAm clocks with …

… of global methylation. Application of DNAm clocks to assess the DNA methylation age would
… In this regard, three DNAm clock versions have been developed for mice, including blood-…

… Our previous work on DNA-methylation-based age estimators (ie, epigenetic clocks) for …
first nonhuman epigenetic clocks. We determined that the age dependence of DNA methylation (…

… properties of such a clock could explain differences in median … We find that discrete DNA
methylation changes correlate with … Importantly, we found that the mouse methylation clock is …

… We hypothesized that our large and diverse DNA methylation data might improve performance
compared to other epigenetic clocks irrespective of model type, adding a confounding …