Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals
… as surrogates for DNA methylation in the brain. Blood, saliva, buccal, and live brain tissue
samples from 27 patients with medically intractable epilepsy undergoing brain resection were …
samples from 27 patients with medically intractable epilepsy undergoing brain resection were …
Cross-tissue correlations of genome-wide DNA methylation in Japanese live human brain and blood, saliva, and buccal epithelial tissues
S Nishitani, M Isozaki, A Yao, Y Higashino… - Translational …, 2023 - nature.com
… For the first time, this study showed the genome-wide DNA methylation differences and
similarities between brain and blood tissues in the same individuals using Illumina 450 K array. …
similarities between brain and blood tissues in the same individuals using Illumina 450 K array. …
[PDF][PDF] Differences in DNA methylation patterns between humans and chimpanzees
… methylation in the brain, 14 are more methylated in humans … methylated in human brains
than in chimpanzee brains. … phenotypic differences, humans and their closest living relatives…
than in chimpanzee brains. … phenotypic differences, humans and their closest living relatives…
Peripheral SLC6A4 DNA Methylation Is Associated with In Vivo Measures of Human Brain Serotonin Synthesis and Childhood Physical Aggression
… processes such as DNA methylation and human behaviours. … in living human subjects
and their epigenetic profile, as brain … First, our current study compared DNA methylation with …
and their epigenetic profile, as brain … First, our current study compared DNA methylation with …
Aging effects on DNA methylation modules in human brain and blood tissue
… [35] showed that MSCs from different tissues exhibit considerable differences in their
DNA methylation profiles, their growth pattern, immunophenotype and in vitro differentiation …
DNA methylation profiles, their growth pattern, immunophenotype and in vitro differentiation …
Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients
LF Wockner, EP Noble, BR Lawford… - Translational …, 2014 - nature.com
… , because it can be readily obtained from living patients. The epigenetic profile differs in the
… differences in methylation status in brain tissue from schizophrenia patients compared with …
… differences in methylation status in brain tissue from schizophrenia patients compared with …
Neuronal activity modifies the DNA methylation landscape in the adult brain
… Given the possibility of reactivation of DNA methylation–silenced retrotransposons in intergenic
regions 40 , we compared methylation patterns of 400 subclasses of repetitive elements …
regions 40 , we compared methylation patterns of 400 subclasses of repetitive elements …
DNA damage response and repair, DNA methylation, and cell death in human neurons and experimental animal neurons are different
LJ Martin, Q Chang - Journal of Neuropathology & Experimental …, 2018 - academic.oup.com
… (A) Phase contrast microscopy of live human neurons generated … among mouse, nonhuman
primate, and human brain cells (96, 98). … Our DNA methylation results support differences in …
primate, and human brain cells (96, 98). … Our DNA methylation results support differences in …
Epigenetic MRI: Noninvasive imaging of DNA methylation in the brain
… , a model with stronger resemblance to human brains than … a DNA-methylation imaging
paradigm for living human brains. … brain hemispheres that revealed strong regional differences in …
paradigm for living human brains. … brain hemispheres that revealed strong regional differences in …
DNA methylation age of human tissues and cell types
S Horvath - Genome biology, 2013 - Springer
… a variety of cell types that can live from months to years. An … change significantly across
different brain regions (temporal … While future studies could account for sequence differences, …
different brain regions (temporal … While future studies could account for sequence differences, …
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