[HTML][HTML] Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

L Chouliaras, D Mastroeni, E Delvaux, A Grover… - Neurobiology of …, 2013 - Elsevier
… with decreased hippocampal 5-mC IR In the present study, we report that 5-mC IR, as a marker
for global DNA methylation, is decreased … a decrease in 5-hmC IR, reflecting global DNA

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
… Epigenetic drift reflects the global decrease in stability and precision of DNA methylation
with age. However, as it is a (epi)genome-wide phenomenon without consistent sites, its …

Rapid DNA methylation changes after exposure to traffic particles

A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
… for traffic pollution, has been consistently associated with a variety of … blood DNA methylation
in repetitive elements was decreased in … In particular, LINE-1 methylation was decreased in …

Genome-wide quantitative assessment of variation in DNA methylation patterns

H Xie, M Wang, A De Andrade, MF Bonaldo… - Nucleic acids …, 2011 - academic.oup.com
… is consistent with previous observation that tumor cells are with decreased fidelity in DNA
methylation … features associated with methylation variations in this study is consistent with the …

DNA methylation in aging of mice

RP Singhal, LL Mays-Hoopes, GL Eichhorn - Mechanisms of ageing and …, 1987 - Elsevier
DNA composition of different age groups is very consistent in … However, a consistent
gradual decline in mSdC content is … aging cattle, DNA methylation decreases in several organs …

Dynamics, stability and inheritance of somatic DNA methylation imprints

LB Sontag, MC Lorincz, EG Luebeck - Journal of theoretical biology, 2006 - Elsevier
methylation that is consistent … as methylation levels decrease. Although the interaction
among the Dnmt's is still only poorly understood, our model posits a mechanism that is consistent

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

V Bollati, J Schwartz, R Wright, A Litonjua… - Mechanisms of ageing …, 2009 - Elsevier
… with decreases in Alu methylation, while results for LINE-1 methylation were less consistent.
… In our data, the decrease in DNA methylation of Alu element over time was relatively small, …

Patterns of reliability: assessing the reproducibility and integrity of DNA methylation measurement

K Sugden, EJ Hannon, L Arseneault, DW Belsky… - Patterns, 2020 - cell.com
… However, to uncover consistent, replicable signals of DNA methylation dynamics, be it
over time, between populations, or between exposures, measurement reliability is crucial. …

Consistency and variability of DNA methylation in women during puberty, young adulthood, and pregnancy

S Chen, N Mukherjee, VD Janjanam… - Genetics & …, 2017 - journals.sagepub.com
… % of CpGs showing a decrease in methylation from age 0 to … P values for testing the
consistency of 218 222 CpG sites used … Manhattan plot for consistency of DNA methylation

Intra-individual change over time in DNA methylation with familial clustering

HT Bjornsson, MI Sigurdsson, MD Fallin, RA Irizarry… - Jama, 2008 - jamanetwork.com
… found no difference in DNA methylation related to age, although … study to date found no
consistent methylation changes at 2 … , since 7 of the 13 most extreme decreases in methylation