[HTML][HTML] Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients
L Chouliaras, D Mastroeni, E Delvaux, A Grover… - Neurobiology of …, 2013 - Elsevier
… with decreased hippocampal 5-mC IR In the present study, we report that 5-mC IR, as a marker
for global DNA methylation, is decreased … a decrease in 5-hmC IR, reflecting global DNA …
for global DNA methylation, is decreased … a decrease in 5-hmC IR, reflecting global DNA …
DNA methylation and healthy human aging
… Epigenetic drift reflects the global decrease in stability and precision of DNA methylation
with age. However, as it is a (epi)genome-wide phenomenon without consistent sites, its …
with age. However, as it is a (epi)genome-wide phenomenon without consistent sites, its …
Rapid DNA methylation changes after exposure to traffic particles
A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
… for traffic pollution, has been consistently associated with a variety of … blood DNA methylation
in repetitive elements was decreased in … In particular, LINE-1 methylation was decreased in …
in repetitive elements was decreased in … In particular, LINE-1 methylation was decreased in …
Genome-wide quantitative assessment of variation in DNA methylation patterns
H Xie, M Wang, A De Andrade, MF Bonaldo… - Nucleic acids …, 2011 - academic.oup.com
… is consistent with previous observation that tumor cells are with decreased fidelity in DNA
methylation … features associated with methylation variations in this study is consistent with the …
methylation … features associated with methylation variations in this study is consistent with the …
DNA methylation in aging of mice
RP Singhal, LL Mays-Hoopes, GL Eichhorn - Mechanisms of ageing and …, 1987 - Elsevier
… DNA composition of different age groups is very consistent in … However, a consistent
gradual decline in mSdC content is … aging cattle, DNA methylation decreases in several organs …
gradual decline in mSdC content is … aging cattle, DNA methylation decreases in several organs …
Dynamics, stability and inheritance of somatic DNA methylation imprints
LB Sontag, MC Lorincz, EG Luebeck - Journal of theoretical biology, 2006 - Elsevier
… methylation that is consistent … as methylation levels decrease. Although the interaction
among the Dnmt's is still only poorly understood, our model posits a mechanism that is consistent …
among the Dnmt's is still only poorly understood, our model posits a mechanism that is consistent …
Decline in genomic DNA methylation through aging in a cohort of elderly subjects
… with decreases in Alu methylation, while results for LINE-1 methylation were less consistent.
… In our data, the decrease in DNA methylation of Alu element over time was relatively small, …
… In our data, the decrease in DNA methylation of Alu element over time was relatively small, …
Patterns of reliability: assessing the reproducibility and integrity of DNA methylation measurement
… However, to uncover consistent, replicable signals of DNA methylation dynamics, be it
over time, between populations, or between exposures, measurement reliability is crucial. …
over time, between populations, or between exposures, measurement reliability is crucial. …
Consistency and variability of DNA methylation in women during puberty, young adulthood, and pregnancy
… % of CpGs showing a decrease in methylation from age 0 to … P values for testing the
consistency of 218 222 CpG sites used … Manhattan plot for consistency of DNA methylation …
consistency of 218 222 CpG sites used … Manhattan plot for consistency of DNA methylation …
Intra-individual change over time in DNA methylation with familial clustering
… found no difference in DNA methylation related to age, although … study to date found no
consistent methylation changes at 2 … , since 7 of the 13 most extreme decreases in methylation …
consistent methylation changes at 2 … , since 7 of the 13 most extreme decreases in methylation …
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