DNA methylation and chromatin structure: the puzzling CpG islands

P Caiafa, M Zampieri - Journal of cellular biochemistry, 2005 - Wiley Online Library
… that these regions are termed CpG islands because they are … for enzymes involved in DNA
methylation. Anomalous insertion of … CpG islands, which remain protected from methylation in …

CpG islands

F Antequera, A Bird - DNA methylation: molecular biology and biological …, 1993 - Springer
… Consistent failure to methylate any region of DNA in the germline would automatically lead
to CpG island-like properties at that sequence, since CpGs would not be methylated and …

DNA methylation: TET proteins—guardians of CpG islands?

K Williams, J Christensen, K Helin - EMBO reports, 2012 - embopress.org
… adjusting methylation levels, and it is largely unknown what prevents the accumulation of
DNA methylation at CpG islands. Importantly, despite an intense search, no direct DNA

DNA methylation profiles of CpG islands for cellular differentiation and development in mammals

K Shiota - Cytogenetic and genome research, 2004 - karger.com
methylated regions (T-DMR), which are potential methylation … -DMRs in CpG islands revealed
that the DNA methylation profile … Differentiation of cells is associated with both methylation

[HTML][HTML] DNA motifs associated with aberrant CpG island methylation

FA Feltus, EK Lee, JF Costello, C Plass, PM Vertino - Genomics, 2006 - Elsevier
DNA pattern recognition and supervised learning techniques, we found that methylation-prone
and methylation-resistant CpG islands could … of CpG islands to aberrant DNA methylation. …

Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters

L Shen, Y Kondo, Y Guo, J Zhang, L Zhang… - PLoS …, 2007 - journals.plos.org
DNA methylation profiling of promoter regions in normal peripheral blood by methylated
CpG island … This technique allowed us to simultaneously determine the methylation status of …

The DNA methylation paradox

PA Jones - Trends in genetics, 1999 - cell.com
… in which a methylated CpG island has been shown to become demethylated after implantation.
Therefore, the data are most consistent with the idea that CpG island methylation acts as …

[HTML][HTML] Distribution of DNA methylation, CpGs, and CpG islands in human isochores

A Varriale, G Bernardi - Genomics, 2010 - Elsevier
… of CpG islands to the ratio of CpG frequency over methylation, we downloaded the file of the
coordinates of the CpG islands … We then filtered these “putative” islands with the criteria of …

Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

BC Christensen, EA Houseman, CJ Marsit… - PLoS …, 2009 - journals.plos.org
… , highly significant CpG island–dependent correlations between age and methylation; loci
in CpG islands gained methylation with age, loci not in CpG islands lost methylation with age (…

[HTML][HTML] CpG islands–'a rough guide'

RS Illingworth, AP Bird - FEBS letters, 2009 - Elsevier
… Mammalian genomes are punctuated by DNA sequences containing an atypically high
frequency of CpG sites termed CpG islands (CGIs). CGIs generally lack DNA methylation and …