… common defect might be able to give rise to the diverse array of defective DNA methylation
… It should be noted that I focus only on those diseases for which defective DNA methylation …

… These disorders of defective DNA methylation highlight the importance of chromosomal
modification for gene control and development. Accumulating observations emphasize the need …

… ) and leads to defects in gene silencing and differentiation [20]. Dicer-deficient mice display
decreased expression of Dnmts and global DNA methylation defects leading to telomere …

… de novo RNA-dependent DNA methylation that is frequently … Although the frequency with
which DNA methylation can be … against transgenerational epigenetic defects. This mechanism …

… It is important to stress that tumors exhibit a global defect in the DNA methylation system with
hypo- and hypermethylation events occurring in the same cell (Figure 3). The reason for the …

… DNA methylation can be carcinogenic and that turnout cells are altered in DNA methylation.
… in gene expression by altering the pattern of DNA methylation. Evidence that one or more …

… Although epigenetic field defects, notably DNA methylation … By measuring DNA methylation
in almost half a million CpG … defects in normal tissues adjacent to breast cancers, with these …

… to a genomic methylation defect that … methylation defect of alpha satellites allow the
identification of two types of patients, both showing an undermethylation of classical satellite DNA. …

… In this review, we will focus on DNA methylation, explore the known enzymatic activities …
of DNA methylation patterns, compare the reprogramming dynamics of methylation between …

… defects represent the most common malformation at birth, occurring also in ∼50% of individuals
with Down syndrome. Congenital heart defects … altering DNA methylation in fetal heart …