[HTML][HTML] Review of processing and analysis methods for DNA methylation array data

CS Wilhelm-Benartzi, DC Koestler, MR Karagas… - British journal of …, 2013 - nature.com
differences between the specific groups (such as cases and controls), such as probe-wise
or locus-specific methylation differences; the two terminologies are therefore equivalent when …

[引用][C] Discovery of genome-wide DNA methylation diversity using the M&M algorithm

Y Zhou, B Zhang, M Marra, J Costello, N Lin, B Zhang…

[HTML][HTML] MethylNet: an automated and modular deep learning approach for DNA methylation analysis

JJ Levy, AJ Titus, CL Petersen, Y Chen, LA Salas… - BMC …, 2020 - Springer
… We aimed to compare the highly contributing CpGs to age predictions using MethylNet and
… a KMeans clustering algorithm on a UMAP clustering of CpG Methylation profiles. Each …

Methods for identifying differentially methylated regions for sequence-and array-based data

DP Chen, YC Lin, CSJ Fann - Briefings in functional genomics, 2016 - academic.oup.com
… our understanding of DNA methylation and provided new insights … fields-based algorithm to
predict DNA methylation levels at … M&M identifies DMRs by computing a probability score for …

Latest techniques to study DNA methylation

Q Gouil, A Keniry - Essays in biochemistry, 2019 - portlandpress.com
… tools differ in the underlying algorithms and the … algorithms and training data [79,80]. Similarly
to the principles of base modification detection in PacBio, when no pre-trained algorithms

[HTML][HTML] Combinatorial identification of DNA methylation patterns over age in the human brain

B Torabi Moghadam, M Dabrowski, B Kaminska… - BMC …, 2016 - Springer
… Since the number of samples in different age classes was different, we ran a 100-fold
under-sampling to avoid the bias of classification towards classes with more samples. In under-…

Tools and strategies for analysis of genome-wide and gene-specific DNA methylation patterns

A Chatterjee, EJ Rodger, IM Morison… - Oral biology: molecular …, 2017 - Springer
… However, it is important to be cautious while using these approaches as these algorithms can
… resolving intermediate methylation or small methylation differences between two samples. …

[HTML][HTML] DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

C Angermueller, HJ Lee, W Reik, O Stegle - Genome biology, 2017 - Springer
DNA methylation levels in populations of cells. Recent technological advances have enabled
profiling DNA methylation at … c, d The trained DeepCpG model can be used for different

Quantitative comparison of genome-wide DNA methylation mapping technologies

C Bock, EM Tomazou, AB Brinkman, F Müller… - Nature …, 2010 - nature.com
… was excluded because no algorithm exists that could accurately infer quantitative DNA
premixed nucleotide triphosphates (1 mM dGTP, 10 mM dATP, 1 mM 5′ methylated dCTP). The …

Methods in DNA methylation profiling

T Zuo, B Tycko, TM Liu, HJL Lin, THM Huang - Epigenomics, 2009 - Taylor & Francis
… the array design algorithm Citation[39]. By using the CHARM assay to detect genome-wide …
In addition to demonstrating methylation differences related to cellular transformation, their …