A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data
… For the comparison of DNA methylation levels between … nucleotide resolution DNA-methylation
data for comparisons of … parameter, and several algorithms were developed to shrink the …
data for comparisons of … parameter, and several algorithms were developed to shrink the …
[HTML][HTML] DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing
… age-associated DNA methylation differences in a way that the … libraries were then normalised
to 4 nM using Tris-HCL 10 mM… The unified genotyper algorithm was employed within GATK …
to 4 nM using Tris-HCL 10 mM… The unified genotyper algorithm was employed within GATK …
[HTML][HTML] De novo identification of differentially methylated regions in the human genome
… DNA methylation is widely regarded as the most stable epigenetic … With regards to real data,
we used two experimental comparisons … Even though the BSmooth algorithm takes a similar …
we used two experimental comparisons … Even though the BSmooth algorithm takes a similar …
[HTML][HTML] Whole slide images reflect DNA methylation patterns of human tumors
… We demonstrate that classical machine learning algorithms can associate the DNA methylation
… We show results in two different cancer sites, glioma and renal cell carcinoma (RCC). …
… We show results in two different cancer sites, glioma and renal cell carcinoma (RCC). …
DNA methylation analysis techniques
C Dahl, P Guldberg - Biogerontology, 2003 - Springer
… In this review, we describe different ways of analyzing DNA methylation and outline the …
techniques for gene-specific analysis of DNA methylation. Each of these techniques is limited in …
techniques for gene-specific analysis of DNA methylation. Each of these techniques is limited in …
Tumour class prediction and discovery by microarray-based DNA methylation analysis
P Adorján, J Distler, E Lipscher, F Model… - Nucleic acids …, 2002 - academic.oup.com
… We then trained the learning algorithm (SVM) to recognise the difference between T and B
cell leukaemias (from both patient samples and cell lines) and CD19 + B cells and CD4 + T …
cell leukaemias (from both patient samples and cell lines) and CD19 + B cells and CD4 + T …
Disease prediction by cell-free DNA methylation
… setting, the methylation differences come from the differences in mixing proportions …
reference-based algorithms that specifically designed for gene expression or DNA methylation data, …
reference-based algorithms that specifically designed for gene expression or DNA methylation data, …
[HTML][HTML] Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders
…, J Masters, M Kadour, MJ Friez, MM van Haelst… - Genetics in …, 2021 - nature.com
… -CAN]”), which will compare the impact of DNA methylation analysis as a first-line versus a
… algorithms. As the EKD expands, the reference machine learning–derived algorithms that …
… algorithms. As the EKD expands, the reference machine learning–derived algorithms that …
DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia
L Milani, A Lundmark, A Kiialainen… - Blood, The Journal …, 2010 - ashpublications.org
… This algorithm performs the clustering by a divisive (top-down) procedure, in which the …
Table 3 lists the genes that displayed a median CpG site methylation difference of 0.3 or greater …
Table 3 lists the genes that displayed a median CpG site methylation difference of 0.3 or greater …
[HTML][HTML] Diagnostic utility of genome-wide DNA methylation testing in genetically unsolved individuals with suspected hereditary conditions
E Aref-Eshghi, EG Bend, S Colaiacovo… - The American Journal of …, 2019 - cell.com
… of genome-wide DNA methylation analysis of peripheral blood … of 14 syndromes using DNA
methylation data with full accuracy. … This study demonstrates that genomic DNA methylation …
methylation data with full accuracy. … This study demonstrates that genomic DNA methylation …