Large-scale methylation analysis of human genomic DNA reveals tissue-specific differences between the methylation profiles of genes and pseudogenes

C Grunau, W Hindermann… - Human molecular …, 2000 - academic.oup.com
… Based on this model we propose to use DNA methylation … the algorithm for the search
for conserved methylation sites. A … , dissolved in 10 mM Tris pH 8.0 and stored at –20C (71). …

Targeted DNA methylation analysis by next-generation sequencing

DR Masser, DR Stanford, WM Freeman - JoVE (Journal of Visualized …, 2015 - jove.com
… quantify DNA methylation patterns and differences in DNA … Add one 5 mm stainless steel
bead to each tube containing … When using variant calling algorithms for highly methylated CpG’s…

Quantitative assessment of DNA methylation: potential applications for disease diagnosis, classification, and prognosis in clinical settings

RM Brena, THM Huang, C Plass - Journal of molecular medicine, 2006 - Springer
… measurements generated from in vitro methylated DNA indicate that this algorithm can
yield accurate results for methylation differences of as low as 20%. Although this figure is …

Genetic control of individual differences in gene-specific methylation in human brain

D Zhang, L Cheng, JA Badner, C Chen, Q Chen… - The American Journal of …, 2010 - cell.com
… extensive interindividual differences in DNA methylation of 8590 … Genotypes were called
with the BRLMM-p algorithm (… of annealing buffer (20 mM Tris-acetate, 2 mM Mg-acetate at pH …

Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns

E Schneider, G Pliushch, N El Hajj… - Nucleic acids …, 2010 - academic.oup.com
… The non-parametric Wilcoxon test was then used to compare the pairwise methylation differences
of … More sophisticated algorithms including multiple genes might considerably improve …

Methylation-level inferences and detection of differential methylation with MeDIP-seq data

Y Zhou, J Zhu, M Zhao, B Zhang, C Jiang, X Yang - PLoS One, 2018 - journals.plos.org
… In addition, we analyze a real dataset for DNA methylation. … We attempt to summarize the
algorithm into a model, which will … of the M&M method is to determine differentially methylated

Cell-free DNA-methylation-based methods and applications in oncology

F Galardi, F De Luca, D Romagnoli, C Biagioni… - Biomolecules, 2020 - mdpi.com
DNA is captured by a recombinant GST-MBD fusion protein … of analyzed DNA into eluates
with different methylated CpG … packages that implement algorithms for signal normalization …

iDNA-Methyl: Identifying DNA methylation sites via pseudo trinucleotide composition

Z Liu, X Xiao, WR Qiu, KC Chou - Analytical biochemistry, 2015 - Elsevier
… [88], [89], [90], [91], [92]), here we also provide a graphic comparison of the current predictor
… , indicating a clear improvement of the new predictor in comparison with the existing ones. …

[HTML][HTML] Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration

X Gao, Y Zhang, LP Breitling, H Brenner - Oncotarget, 2016 - ncbi.nlm.nih.gov
DNA methylation ages by two recently proposed algorithms. … In conclusion, DNA
methylation-based biological indicators for … For instance, different smoking associated CpG sites …

Identification of type 1 diabetes–associated DNA methylation variable positions that precede disease diagnosis

VK Rakyan, H Beyan, TA Down, MI Hawa… - PLoS …, 2011 - journals.plos.org
… show intra-MZ pair DNA methylation differences in the expected direction. Indeed, we
observed a statistically significant DNA methylation difference in the expected direction between …