Substantial DNA methylation differences between two major neuronal subtypes in human brain
… CpG methylation. Regions that are differentially methylated in GABA and GLU neurons were
… Collectively, our findings suggest that functional differences between neuronal subtypes are …
… Collectively, our findings suggest that functional differences between neuronal subtypes are …
Principles governing DNA methylation during neuronal lineage and subtype specification
… main conclusion of our work is that the neuronal methylation/… when neuron subtype-specific
differences also emerge. … rules that govern DNA methylation and demethylation in neuronal …
differences also emerge. … rules that govern DNA methylation and demethylation in neuronal …
Evolution of DNA methylation in the human brain
… DNA methylation changes during recent human brain evolution. We demonstrate dynamic
evolutionary trajectories of DNA methylation … methylation patterns of neuronal subtypes for CH …
evolutionary trajectories of DNA methylation … methylation patterns of neuronal subtypes for CH …
DNA methylation profiling of human prefrontal cortex neurons in heroin users shows significant difference between genomic contexts of hyper-and hypomethylation …
A Kozlenkov, AE Jaffe, A Timashpolsky, P Apontes… - Genes, 2017 - mdpi.com
… different neuronal subtypes and different genomic contexts. These observations imply that
different … regulation might be recruited in different neuronal subtypes or specifically targeted to …
different … regulation might be recruited in different neuronal subtypes or specifically targeted to …
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex
… The aim of this study is to address DNA methylation changes … , we performed an initial DNA
methylation screen on unsorted … To calculate the association between DNA methylation and …
methylation screen on unsorted … To calculate the association between DNA methylation and …
Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex
… neuronal diversity in human, revealed by DNA methylation … potential dorsal origin of certain
interneuron subtypes (15, 24, 25). … the DNA methylation–based neuronal populations defined …
interneuron subtypes (15, 24, 25). … the DNA methylation–based neuronal populations defined …
Neuronal activity modifies the DNA methylation landscape in the adult brain
… methylation changes for a defined mature neuronal subtype in vivo. Together with the gene
expression profiles, these data sets will serve as a resource for the neuroscience community. …
expression profiles, these data sets will serve as a resource for the neuroscience community. …
Neuronal cell-type specific DNA methylation patterns of the Cacna1c gene
M Nishioka, T Shimada, M Bundo, W Ukai… - International Journal of …, 2013 - Elsevier
… will be critically important. Here we examined DNA methylation status of CpG islands and
a CpG island shore on mouse Cacna1c in neuronal and non-neuronal nuclei, which were …
a CpG island shore on mouse Cacna1c in neuronal and non-neuronal nuclei, which were …
The role of DNA methylation in the central nervous system and neuropsychiatric disorders
J Feng, G Fan - International review of neurobiology, 2009 - Elsevier
… toxic, subtype … neuronal DNA methylation change under both physiological and pathological
conditions will further improve our understanding of the role of DNA methylation in neural …
conditions will further improve our understanding of the role of DNA methylation in neural …
Cell type-specific DNA methylome signatures reveal epigenetic mechanisms for neuronal diversity and neurodevelopmental disorder
… Our results suggest that cell type-specific DNA methylation signatures are associated with …
the neuronal subtypes. The presented results emphasize the importance of DNA methylation-…
the neuronal subtypes. The presented results emphasize the importance of DNA methylation-…
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