Mathematical models of DNA methylation dynamics: Implications for health and ageing

L Zagkos, M Mc Auley, J Roberts… - Journal of theoretical …, 2019 - Elsevier
… it that DNA methylation dynamics do not alter when the quantity of DNA methylation enzymes
… would be to perform methylation assays using the three methylation enzymes, DNMT1, …

Longitudinal DNA methylation dynamics as a practical indicator in clinical epigenetics

S Komaki, H Ohmomo, T Hachiya, Y Sutoh, K Ono… - Clinical …, 2021 - Springer
DNA methylation data is needed to understand the global nature of DNA methylation dynamics.
… We aimed to provide an insight into the dynamics and interpretations of DNA methylation

DNA methylation 40 years later: Its role in human health and disease

MI Scarano, M Strazzullo, MR Matarazzo… - Journal of cellular …, 2005 - Wiley Online Library
… Here, we review the impact of the studies on DNA methylation, the “primadonna” in the …
The effect of deregulation of DNA methylation on human health, will be also discussed. …

DNA methylation dynamics in health and disease

Y Bergman, H Cedar - Nature structural & molecular biology, 2013 - nature.com
DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established
at the time of implantation. In this Review, dynamics of DNA methylationmethylation

[HTML][HTML] DNA methylation dynamics in aging: how far are we from understanding the mechanisms?

F Ciccarone, S Tagliatesta, P Caiafa… - Mechanisms of ageing …, 2018 - Elsevier
… Individuals that experienced in utero exposure to famine had an increased incidence of
several health problems such as obesity, hypertension, cardiovascular diseases and impaired …

Population DNA methylation studies in the Developmental Origins of Health and Disease (DOHaD) framework

JF Felix, CAM Cecil - … of developmental origins of health and disease, 2019 - cambridge.org
DNA methylation is the most studied epigenetic mechanism … We discuss the application of
DNA methylation in early-life … DNA methylation within the Developmental Origins of Health

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
DNA methylation in age across the lifespan and across tissues. In this review, we outline the
dynamics of DNA methylation … We focus only on healthy aging; for excellent reviews of the …

Dynamic DNA methylation during aging: a “prophet” of age-related outcomes

FH Xiao, HT Wang, QP Kong - Frontiers in genetics, 2019 - frontiersin.org
… to assess the health status of a person. … diseases (eg, Alzheimer’s disease, cardiovascular
disease). In this review, we provide an overview of the dynamic signatures of DNA methylation

DNA methylation dynamics in muscle development and disease

E Carrió, M Suelves - Frontiers in aging neuroscience, 2015 - frontiersin.org
… The aim of the present review is to discuss the major advances concerning the DNA methylation
dynamics during myogenesis and its implications in muscle development and disease. …

Dynamics of DNA methylation in aging and Alzheimer's disease

HA Irier, P Jin - DNA and cell biology, 2012 - liebertpub.com
DNA methylation in neurodegenerative diseases, with a special focus on DNA methylation
dynamics … of neurodegeneration and its potential role in aging and Alzheimer's disease (AD). …