DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm

H Kobayashi, H Hiura, RM John, A Sato… - European journal of …, 2009 - nature.com
… , in some cases, the errors are inherited from the father. We analyzed DNA methylation at
seven autosomal imprinted loci and the XIST locus in 78 paired DNA samples. In seven out of …

DNA methylation errors in imprinting disorders and assisted reproductive technology

H Chiba, H Hiura, H Okae, N Miyauchi… - Pediatrics …, 2013 - Wiley Online Library
… In contrast, only a few of the natural conception patients had similar DNA methylation errors
… The increased frequency and difference of the pattern of DNA methylation errors between …

Characterization of DNA methylation errors in patients with imprinting disorders conceived by assisted reproduction technologies

H Hiura, H Okae, N Miyauchi, F Sato, A Sato… - Human …, 2012 - academic.oup.com
… We collected seven BWS samples with DNA methylation errors of the LIT1 gDMR, one of
which was derived from ART patient and six from naturally conceived patients (Supplementary …

Oxidative stress and alterations in DNA methylation: two sides of the same coin in reproduction

YJR Menezo, E Silvestris, B Dale, K Elder - Reproductive biomedicine …, 2016 - Elsevier
… by DNA methylation and epigenetic errors. Age has a negative effect on oxidative stress and
DNA methylation… also increase oxidative stress and methylation errors. Oxidative stress and …

Rethinking how DNA methylation patterns are maintained

PA Jones, G Liang - Nature Reviews Genetics, 2009 - nature.com
… replication, DNMT3A and DNMT3B complete the methylation process and correct errors
that are left by the DNMT1 enzyme. Because these enzymes are compartmentalized to the …

DNA methylation

MG Marinus, A Løbner-Olesen - EcoSal Plus, 2014 - Am Soc Microbiol
… (DNA adenine methyltransferase) and dcm (DNA cytosine methyltransferase) genes. Although
not essential, Dam methylation … the repair of replication errors, controlling the frequency of …

Imprinting methylation errors in ART

H Hiura, H Okae, H Chiba, N Miyauchi, F Sato… - … medicine and biology, 2014 - Springer
… 10 natural) with DNA methylation errors at H19 DMR, and 7 BWS (1 ART and 6 natural) with
DNA methylation errors of the LIT1 DMR, and compared the DNA methylation status. In most …

DNA repair and the control of DNA methylation

P Schär, O Fritsch - Epigenetics and Disease: Pharmaceutical …, 2011 - Springer
methylation in cancer illustrates the importance of quality control in the DNA methylation
These observations suggest that methylation errors are mainly due to de novo methylation

Analysing and interpreting DNA methylation data

C Bock - Nature Reviews Genetics, 2012 - nature.com
… Bis-SNP also removes a common error source in the analysis of DNA methylation data, as
it can distinguish bisulphite-induced changes from genetic variants. This is possible because …

DNA methylation analysis: a review of current methodologies

EJ Oakeley - Pharmacology & therapeutics, 1999 - Elsevier
… The best way to minimise such errors is to digest the DNA with a restriction enzyme that
does not contain a CpG sequence in its recognition site and then phenol:chloroform extract it …