[HTML][HTML] Role of DNA methylation in stable gene repression
L Lande-Diner, J Zhang, I Ben-Porath… - Journal of Biological …, 2007 - ASBMB
… DNA methylation on both gene expression and chromatin structure. Our results confirm that
the underlying methylation … that many methylated genes are subject to additional repression …
the underlying methylation … that many methylated genes are subject to additional repression …
DNA methylation and silencing of gene expression
J Newell-Price, AJL Clark, P King - Trends in Endocrinology & Metabolism, 2000 - cell.com
… How does the methylated DNA interfere with gene transcription? Within the past two years,
… of the mechanisms whereby this transcriptional repression is mediated, with particular …
… of the mechanisms whereby this transcriptional repression is mediated, with particular …
How does DNA methylation repress transcription?
… the repressive chromatin structure. Although we focus on molecular mechanisms that might
influence DNA methylation and gene expression in dividing cells, DNA demethylation is also …
influence DNA methylation and gene expression in dividing cells, DNA demethylation is also …
[HTML][HTML] DNA methylation and its basic function
LD Moore, T Le, G Fan - Neuropsychopharmacology, 2013 - nature.com
… DNA methylation regulates gene expression by recruiting proteins involved in gene repression
… In this review, we will discuss the basic function of DNA methylation in epigenetic gene …
… In this review, we will discuss the basic function of DNA methylation in epigenetic gene …
DNA methylation and the regulation of gene transcription
JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
… Interestingly, MBD2 has been found in association with both Sin3A [113] and also the Mi2/NuRD
complex [112], and is likely to play a role in gene repression mediated by both Sin3A …
complex [112], and is likely to play a role in gene repression mediated by both Sin3A …
Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl‐CpG binding protein.
J Boyes, A Bird - The EMBO journal, 1992 - embopress.org
… of this sparsely methylated promoter was in fact … of DNA methylation on transcription of
CpG-deficient genes, using promoters of different strengths to gauge the severity of repression. …
CpG-deficient genes, using promoters of different strengths to gauge the severity of repression. …
DNA methylation in the gene body influences MeCP2-mediated gene repression
B Kinde, DY Wu, ME Greenberg… - Proceedings of the …, 2016 - National Acad Sciences
… DNA methylation across genes and provide evidence that the degree of repression experienced
by each gene … within the transcribed region of the gene. Taken together, these findings …
by each gene … within the transcribed region of the gene. Taken together, these findings …
DNA methylation
R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… Repression of transcription from densely methylated genes … 1 show much reduced
repression of methylated genes.50 In a … that sparse methylation could repress transfected genes …
repression of methylated genes.50 In a … that sparse methylation could repress transfected genes …
[引用][C] The essentials of DNA methylation
A Bird - cell, 1992 - Elsevier
… DNA methylation can stably repress transcription, it could be that repression is leaky in the
absence of DNA … The stability of gene repression on the inactive X chromosome in somatic …
absence of DNA … The stability of gene repression on the inactive X chromosome in somatic …
Molecular mechanisms of gene silencing mediated by DNA methylation
M Curradi, A Izzo, G Badaracco… - Molecular and cellular …, 2002 - Am Soc Microbiol
… Histone deacetylation is the main cause of gene repression only when methylation does not
… In most cases, DNA methylation seems to repress gene expression by recruiting binding …
… In most cases, DNA methylation seems to repress gene expression by recruiting binding …
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