… with histone deacetylase. These observations firmly connect DNA methylation with …
They also provide new pathways for the potential targeting of DNA methylation to repressive …

… to DNA methylation – methyl-CpG-binding domain proteins (MBDs) and histone deacetylases
(… supporting a role for DNA methylation and histone deacetylation in nervous system …

… Critical to the epigenetic therapy focus of this review is the link of HDACs 1 and 2 to the
DNA methylation processes discussed earlier. These two proteins, as mentioned earlier and …

… Our results indicate that in higher organisms DNA methylation may serve as a unique
mechanism for setting up local histone deacetylation, and so generate maintainable epigenetic …

… Other evidence exists that DNA methylation and histone deacetylation interact to maintain
a repressive chromatin complex at the ERα promoter. Inhibition of either may be sufficient to …

… genes silenced by promoter methylation (7). DAC inhibits DNA methylation by reducing the
… a stable complex between the enzyme and DAC-substituted DNA (13). One difficulty in using …

… link between DNA methylation, histone deacetylation and … mechanism by which DNA
methylation contributes to both … of chromatin remodelling and deacetylase activities. The Mi-2 …

… -specific histone deacetylase that … deacetylation and subsequent H3 lysine 9 methylation.
Collectively, the data support a model in which cytosine methylation and histone deacetylation …

… by DNA methylation at the gene’s promoter and by histone deacetylation in the region
containing the gene, with inhibition of DNA methylation or of histone deacetylation reversing the …

… include histone deacetylases (HDACs). In addition, … DNA methylation meets histone
acetylation Although evidence for involvement of histone hypoacetylation and/or DNA methylation in …