Genome-wide analysis of DNA methylation dynamics during early human development
H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
… reported partial methylomes of human gametes and early … of DNA methylation dynamics
during early human development, we report on whole genome bisulfite sequencing of human …
during early human development, we report on whole genome bisulfite sequencing of human …
DNA methylation signatures in development and aging of the human prefrontal cortex
S Numata, T Ye, TM Hyde, X Guitart-Navarro… - … Journal of Human …, 2012 - cell.com
… DNA methylation is strongly associated with genotypic variants and … development and in
de novo DNA methylation. Our results indicate that promoter DNA methylation in the human …
de novo DNA methylation. Our results indicate that promoter DNA methylation in the human …
DNA methylation in early development
A Razin, R Shemer - Human Molecular Genetics, 1995 - academic.oup.com
… DNA methylation is involved in embryo development. … develop to term and die at the 5 to
20 somite stage corresponding to the level of the enzyme. In the mouse, dramatic methylation …
20 somite stage corresponding to the level of the enzyme. In the mouse, dramatic methylation …
[HTML][HTML] DNA methylation and histone deacetylation in the control of gene expression: basic biochemistry to human development and disease
A El-Osta, AP Wolffe - Gene expression, 2000 - ncbi.nlm.nih.gov
… DNA methylation is a major determinant in the epigenetic silencing of genes. The … of DNA
methylation and the subsequent repression of transcription are relevant to human development …
methylation and the subsequent repression of transcription are relevant to human development …
DNA methylation landscapes of human fetal development
RC Slieker, MS Roost, L van Iperen… - PLoS …, 2015 - journals.plos.org
… human diseases. This organ-specific catalogue of DNA methylation during development
provides fundamental insights into processes guiding human development, but also into the …
provides fundamental insights into processes guiding human development, but also into the …
DNA methylation in development and human disease
S Gopalakrishnan, BO Van Emburgh… - … Molecular Mechanisms of …, 2008 - Elsevier
… development and carcinogenesis. In this review, we summarize the recent studies in DNA
methylation … their potential role in gene silencing in development and disease. Although the …
methylation … their potential role in gene silencing in development and disease. Although the …
DNA methylation and healthy human aging
… changes in DNA methylation throughout later childhood and adolescence. Studies that
examined this period of human development have reported that DNA methylation levels increase …
examined this period of human development have reported that DNA methylation levels increase …
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
… The DNA methylation pattern observed at W22 in some organs … of human fetal DNA
methylation and corresponding genome-wide transcription data: the analysis includes 21 human …
methylation and corresponding genome-wide transcription data: the analysis includes 21 human …
DNA methylation in early development
TM Geiman, K Muegge - … Reproduction and Development …, 2010 - Wiley Online Library
… in development to put it in the context of human developmental diseases. Defects in DNA
methylation or the interpretation of the DNA methyl mark can lead to several developmental …
methylation or the interpretation of the DNA methyl mark can lead to several developmental …
Postnatal development-and age-related changes in DNA-methylation patterns in the human genome
P Salpea, VR Russanova, TH Hirai… - Nucleic acids …, 2012 - academic.oup.com
… Alterations in DNA methylation have been reported to occur during development and aging;
… few if any investigations have compared human methylome patterns on a whole genome …
… few if any investigations have compared human methylome patterns on a whole genome …
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