Establishment and functions of DNA methylation in the germline
KR Stewart, L Veselovska, G Kelsey - Epigenomics, 2016 - Taylor & Francis
… This is best understood for DNA methylation which, established at discrete regions of the …
informed our understanding of de novo DNA methylation mechanisms, highlight how recent …
informed our understanding of de novo DNA methylation mechanisms, highlight how recent …
DNA methylation dynamics during germline development
… In animals, DNA methylation is also developmentally … the understanding that DNA methylation
plays a similar role in … dynamic changes in DNA methylation during germline development. …
plays a similar role in … dynamic changes in DNA methylation during germline development. …
Environmental impact on DNA methylation in the germline: state of the art and gaps of knowledge
F Pacchierotti, M Spanò - BioMed research international, 2015 - Wiley Online Library
… related DNA methylation … germline, even by the analysis of easily accessible sperm. In this
paper, we review the state of the art on factors impinging on DNA methylation in the germline, …
paper, we review the state of the art on factors impinging on DNA methylation in the germline, …
DNA methylation reprogramming in the germ line
DJ Lees-Murdock, CP Walsh - Epigenetics, 2008 - Taylor & Francis
… In addition to direct transcriptional silencing, DNA methylation is important for … of DNA
methylation reprogramming of many different sequence classes. We focus on the mouse germline, …
methylation reprogramming of many different sequence classes. We focus on the mouse germline, …
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… of DNA methylation inheritance through semiconservative DNA replication, which implied
two … modes of DNA methylation activity: maintenance methylation and de novo methylation (…
two … modes of DNA methylation activity: maintenance methylation and de novo methylation (…
Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of …
C Tayama, V Romanelli, A Martin-Trujillo… - Genome …, 2014 - genome.cshlp.org
… BeadChip arrays to generate methylation profiles. To validate this approach, we compared
the DNA methylation profiles generated by each method. Methylation scores produced by the …
the DNA methylation profiles generated by each method. Methylation scores produced by the …
The impact of DNA methylation dynamics on the mutation rate during human germline development
Y Zhou, F He, W Pu, X Gu, J Wang… - G3: Genes, Genomes …, 2020 - academic.oup.com
… Our study provides evidence that DNA methylation in germline relevant cells has a … DNA
methylation levels mentioned in this study are specifically referred to as the DNA methylation …
methylation levels mentioned in this study are specifically referred to as the DNA methylation …
Germline-derived DNA methylation and early embryo epigenetic reprogramming: the selected survival of imprints
D Monk - The international journal of biochemistry & cell biology, 2015 - Elsevier
DNA methylation is an essential epigenetic mechanism involved in many essential cellular
processes. During development epigenetic reprograming takes place during gametogenesis …
processes. During development epigenetic reprograming takes place during gametogenesis …
Germline DNA methylation in reef corals: patterns and potential roles in response to environmental change
JL Dimond, SB Roberts - Molecular Ecology, 2016 - Wiley Online Library
… DNA methylation and gene function. In this study, we performed a comprehensive evaluation
of germline methylation … Germline methylation levels in these data were inferred based on …
of germline methylation … Germline methylation levels in these data were inferred based on …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… We highlight the dynamic erasure and re-establishment of DNA methylation in embryonic,
germline and somatic cell development. Finally, we provide insights into DNA methylation …
germline and somatic cell development. Finally, we provide insights into DNA methylation …
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