Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

M Weber, I Hellmann, MB Stadler, L Ramos, S Pääbo… - Nature …, 2007 - nature.com
… We conclude that somatic cells show a systematic methylation of promoters for germline-specific
genes, including strong CpG islands that are otherwise protected from …

DNA methylation reprogramming of genomic imprints in the mammalian germline: A TET‐centric view

BA Caldwell, MS Bartolomei - Andrology, 2023 - Wiley Online Library
… that are critical to achieving a DNA hypomethylated state, with … DNA methylation dynamics
in the mammalian genome, with a particular emphasis on DNA demethylation in the germline

Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer

A Hazra, CS Fuchs, T Kawasaki, GJ Kirkner… - Cancer causes & …, 2010 - Springer
… CpG island methylation in colorectal … germline nonsynonymous SNPs (nsSNPs) in 12
one-carbon metabolism genes and DNA methylation status (CIMP status and LINE-1 methylation) …

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

N Grabole, J Tischler, JA Hackett, S Kim, F Tang… - EMBO …, 2013 - embopress.org
… gene family that are regulated by their promoter DNA methylation [12, 13], were … of DNA
methyltransferases is necessary for their expression. We confirmed retention of DNA methylation

De novo DNA methylation: a germ cell perspective

SA Smallwood, G Kelsey - Trends in Genetics, 2012 - cell.com
… Elucidating how DNA methylation marks are established in the germline has been a
challenge for nearly 20 years, but represents a key step towards a full understanding of several …

[HTML][HTML] Sequences sufficient for programming imprinted germline DNA methylation defined

YJ Park, H Herman, Y Gao, AM Lindroth, BY Hu… - PloS one, 2012 - journals.plos.org
DNA methylation from the maternal allele [18]. H19 DNA methylation acquired in the germline
… is necessary for establishing methylation at the adjacent DMD in the male germline [22]. …

[HTML][HTML] High-fat diet-induced and genetically inherited obesity differentially alters DNA methylation profile in the germline of adult male rats

SS Deshpande, H Nemani, G Arumugam… - Clinical …, 2020 - Springer
… To study the effect of high-fat diet-induced and genetically inherited obesity on DNA methylation
in the male germline, we first assessed the DNA methyltransferases expression pattern …

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development

R Yan, X Cheng, C Gu, Y Xu, X Long, J Zhai, F Sun… - Nature Genetics, 2023 - nature.com
… novo or maintenance DNA methylation in mouse zygotes remains debatable 9 . Moreover,
although a small repertoire of maternal genes are known to affect DNA methylation in mouse …

DNA methylation-associated repression of cancer-germline genes in human embryonic and adult stem cells

A Loriot, S Reister, GK Parvizi, PA Lysy, C De Smet - Stem Cells, 2009 - academic.oup.com
… Cancer-germline (CG) genes are a particular group of germline-specific genes that rely
primarily on DNA methylation for repression in somatic tissues. In a wide variety of tumors, the …

[HTML][HTML] DNA methylation imprints on the IG-DMR of the Dlk1–Gtl2 domain in mouse male germline

H Hiura, J Komiyama, M Shirai, Y Obata, H Ogawa… - FEBS letters, 2007 - Elsevier
… and Gtl2 is specifically methylated in the male germline; IG-DMR regulates the parental …
methylation marks during male germ-cell differentiation. For parental allele-specific methylation