Comparison of RNA m6A and DNA methylation profiles between mouse female germline stem cells and STO cells

X Zhao, GG Tian, Q Fang, X Pei, Z Wang… - Molecular Therapy-Nucleic …, 2021 - cell.com
… female germline stem cells (mFGSCs) have been published. In this study, we compared the
genome-wide profiles of mRNA m 6 A methylation and DNA methylation … of methylated DNA

Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome

J Li, RA Harris, SW Cheung, C Coarfa, M Jeong… - PLoS …, 2012 - journals.plos.org
… We examine associations of structural mutability with germline DNA methylation and with
non-allelic homologous recombination (NAHR) mediated by low-copy repeats (LCRs). …

Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… panel of germline genes. While we and others previously found some germline genes reactivated
… that the set of germline genes repressed by CpG-island DNA methylation is larger than …

Transcription is required for establishment of germline methylation marks at imprinted genes

M Chotalia, SA Smallwood, N Ruf… - Genes & …, 2009 - genesdev.cshlp.org
… In this study, we provide evidence that transcriptional events are required for the establishment
of DNA methylation imprints in the female germline. Functional evidence in support of this …

Epigenetic processes in the male germline

AM O'Doherty, PA McGettigan - Reproduction, Fertility and …, 2015 - CSIRO Publishing
… Similar to establishment of germline DNA methylation patterns, the dynamics of … In this
article, reprogramming of the male germline DNA methylation marks is emphasised. The paternal …

Targets and dynamics of promoter DNA methylation during early mouse development

J Borgel, S Guibert, Y Li, H Chiba, D Schübeler… - Nature …, 2010 - nature.com
… Our data reveals that one important function of DNA methylation is to repress the germline
expression program in developing embryos in vivo. Previous studies have identified …

DNA methylation in genomic imprinting, development, and disease

M Paulsen, AC Ferguson‐Smith - The Journal of pathology, 2001 - Wiley Online Library
DNA methylation can regulate gene expression, using imprinted genes as examples. The
molecular basis of methylation-… The methylation pattern is germline-specific: sperm DNA is …

Heritable germline epimutations in humans

B Horsthemke - Nature genetics, 2007 - nature.com
… Epigenetic marks such as DNA methylation and histone modification allow the transmission
… these marks can also be transmitted through the germline. If so, an aberrant epigenetic mark …

Refurbishing the germline epigenome: out with the old, in with the new

K Hogg, PS Western - Seminars in cell & developmental biology, 2015 - Elsevier
… Indeed, deletion of germline Setdb1 results in loss of DNA methylation and the repressive …
of DNA methylation and probably other epigenetic modifications is essential during germline

Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks

H Kobayashi, T Sakurai, M Imai, N Takahashi… - PLoS …, 2012 - journals.plos.org
… Genome-wide dynamic changes in DNA methylation are indispensable for germline
development and genomic imprinting in mammals. Here, we report single-base resolution …