The DNA methylation landscape in cancer
… and advances to distinguish major and minor DNA methylation intermediates such as 5hmC
from 5mC [15,16], the field is building comprehensive maps of DNA methylation landscapes…
from 5mC [15,16], the field is building comprehensive maps of DNA methylation landscapes…
DNA methylation landscapes: provocative insights from epigenomics
MM Suzuki, A Bird - Nature reviews genetics, 2008 - nature.com
… methylated, as are gene bodies and intergenic DNA. e | The DNA methylation landscape of
… that genes are separated by long tracts of DNA that contain transposable elements and their …
… that genes are separated by long tracts of DNA that contain transposable elements and their …
Charting a dynamic DNA methylation landscape of the human genome
… In this study, we systematically investigated the DNA methylation state of most human … On
a global scale, human ES cells and their derivatives exhibit the highest DNA methylation levels…
a global scale, human ES cells and their derivatives exhibit the highest DNA methylation levels…
The DNA methylation landscape of advanced prostate cancer
… Although DNA methylation is a key regulator of gene expression, the comprehensive
methylation landscape of metastatic cancer has never been defined. Through whole-genome …
methylation landscape of metastatic cancer has never been defined. Through whole-genome …
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[HTML][HTML] Navigating the DNA methylation landscape of cancer
A Nishiyama, M Nakanishi - Trends in Genetics, 2021 - cell.com
… DNA methylation patterns are maintained by the daughter DNA through a maintenance
DNA methylation … Both de novo DNA methylation and maintenance DNA methylation are …
DNA methylation … Both de novo DNA methylation and maintenance DNA methylation are …
The DNA methylation landscape of human early embryos
H Guo, P Zhu, L Yan, R Li, B Hu, Y Lian, J Yan, X Ren… - Nature, 2014 - nature.com
… a, Averaged DNA methylation levels along the gene bodies and 15 kilobases (kb) … b,
Methylation landscape across each stage of human early embryos. The averaged DNA methylation …
Methylation landscape across each stage of human early embryos. The averaged DNA methylation …
Neuronal activity modifies the DNA methylation landscape in the adult brain
… Our study shows how the epigenetic DNA methylation landscape of mature neurons is rapidly
modified in response to external stimuli in vivo. Recent technical advances have enabled …
modified in response to external stimuli in vivo. Recent technical advances have enabled …
An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging
… integrating Illumina 450k DNA methylation with ENCODE data … that genome-wide DNA
methylation patterns change with age [1–… of the DNA methylation landscape in response to aging. …
methylation patterns change with age [1–… of the DNA methylation landscape in response to aging. …
The DNA methylation landscape of hematological malignancies: an update
P Blecua, L Martinez‐Verbo, M Esteller - Molecular Oncology, 2020 - Wiley Online Library
… DNA methylation is a key epigenetic player in … DNA methylation in hematological malignancies
described in the current literature. We discuss in detail the dual role of DNA methylation …
described in the current literature. We discuss in detail the dual role of DNA methylation …
The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space
… of DNA methylation sequencing in large cohorts of routinely collected clinical FFPE tumor
samples. To put the DNA methylation data … us to identify DNA methylation patterns predictive of …
samples. To put the DNA methylation data … us to identify DNA methylation patterns predictive of …