DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations

J Gallon, A Rodriguez-Calero, A Benjak… - Cancer research, 2023 - AACR
DNA methylation landscapes of PCBM and the potential mechanisms and effects of
PCBM-associated aberrant DNA methylation… Here, we present the DNA methylation landscapes of …

The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells

S Kalari, M Jung, KH Kernstine, T Takahashi… - Oncogene, 2013 - nature.com
DNA methylation changes found in SCLC tumors, have not been studied so far in a
comprehensive manner. DNA methylation … There are several gene-specific DNA methylation

[HTML][HTML] Repeat elements and the Arabidopsis DNA methylation landscape

FK Teixeira, V Colot - Heredity, 2010 - nature.com
… model for the study of DNA methylation and its inheritance patterns in higher eukaryotes.
Here, we review our current understanding of DNA methylation in Arabidopsis, with particular …

[HTML][HTML] The DNA methylation landscape of giant viruses

S Jeudy, S Rigou, JM Alempic, JM Claverie… - Nature …, 2020 - nature.com
… We show that DNA methylation is widespread, affecting 2/3 of the … used to study the methylation
landscapes of isolated bacteria … Our findings reveal that DNA methylation is widespread …

Combined SOM-portrayal of gene expression and DNA methylation landscapes disentangles modes of epigenetic regulation in glioblastoma

L Hopp, H Löffler-Wirth, J Galle, H Binder - Epigenomics, 2018 - Future Medicine
Aim: We present here a novel method that enables unraveling the interplay between gene
expression and DNA methylation in complex diseases such as cancer. Materials & methods: …

Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis

DM Marzese, RA Scolyer, JL Huynh… - Human molecular …, 2014 - academic.oup.com
… Alteration in DNA methylation is a major hallmark of tumor progression and metastasis; …
DNA methylation landscape through the use of genome-wide copy number, DNA methylation

[HTML][HTML] The DNA methylation landscape of multiple myeloma shows extensive inter-and intrapatient heterogeneity that fuels transcriptomic variability

J Derrien, C Guérin-Charbonnel, V Gaborit… - Genome medicine, 2021 - Springer
… To explore the disrupted DNA methylation landscape in MM, … We found that the aberrant
DNA methylation is associated with … the importance of the DNA methylation disruption on inter- …

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool… - Nature, 2014 - nature.com
… , with re-establishment of the DNA methylation pattern typical of other genomic regions. DMVs
… We demonstrate, however, that cancer-specific gain of DNA methylation in DMVs is also …

The landscape of DNA methylation amid a perfect storm of autism aetiologies

AV Ciernia, J LaSalle - Nature reviews neuroscience, 2016 - nature.com
… Epigenetic mechanisms such as DNA methylationDNA methylation are providing valuable
mechanistic insights into ASD. The dynamic developmental landscape of DNA methylation is …

Sex‐specific changes in the aphid DNA methylation landscape

TC Mathers, ST Mugford, L Percival‐Alwyn… - Molecular …, 2019 - Wiley Online Library
… Taken together, our findings suggest a role for DNA methylation in the regulation of aphid
gene expression, and that methylation is intrinsically linked to sexual dimorphism in aphids. …