Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cells
R Massart, S Dymov, M Millecamps, M Suderman… - Scientific reports, 2016 - nature.com
… Genome-wide DNA methylation assessed in 9 months … DNA methylation landscape in the
brain between the groups and a remarkable overlap (72%) between differentially methylated …
brain between the groups and a remarkable overlap (72%) between differentially methylated …
DNA methylation: a promising landscape for immune system-related diseases
B Suarez-Alvarez, RM Rodriguez, MF Fraga… - Trends in Genetics, 2012 - cell.com
… describe how the DNA methylation patterns are … DNA methylation, which is essential for
the stability of gene expression during hematopoiesis. Furthermore, aberrant DNA methylation …
the stability of gene expression during hematopoiesis. Furthermore, aberrant DNA methylation …
Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus
… In this work, we investigate the influence of ENR on DNA methylation patterns in the
hippocampal dentate gyrus and find that ENR counteracts aging-induced DNA methylation changes …
hippocampal dentate gyrus and find that ENR counteracts aging-induced DNA methylation changes …
[PDF][PDF] Pan-cancer landscape of aberrant DNA methylation across human tumors
… in specific pathways including apoptosis, DNA repair, and cell … approach to explore DNA
methylation changes in pediatric … cancer map of aberrant DNA methylation to inform functional …
methylation changes in pediatric … cancer map of aberrant DNA methylation to inform functional …
Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape
K Day, LL Waite, A Thalacker-Mercer, A West… - Genome biology, 2013 - Springer
… tissue-specific DNA methylation changes with age that are reflective of CpG landscape and
… epigenetic drift model is insufficient to explain all age-related changes in DNA methylation. …
… epigenetic drift model is insufficient to explain all age-related changes in DNA methylation. …
Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape
… DNA methylation (DNAme) is globally erased during migration of primordial germ cells (…
by de novo establishment of new methylation landscapes that are different between male and …
by de novo establishment of new methylation landscapes that are different between male and …
Genomic landscape of human allele-specific DNA methylation
… DNA methylation … of DNA methylation, existing methylome data remain largely untapped
in the study of imprinting. We present a statistical model to describe allele-specific methylation (…
in the study of imprinting. We present a statistical model to describe allele-specific methylation (…
Loss of DNA methylation affects the recombination landscape in Arabidopsis
M Mirouze, M Lieberman-Lazarovich… - Proceedings of the …, 2012 - National Acad Sciences
… To determine by which mechanisms altered levels of DNA methylation influence … , suggest
that DNA methylation affects meiotic recombination in cis. Because DNA methylation exhibits …
that DNA methylation affects meiotic recombination in cis. Because DNA methylation exhibits …
DNA methylation disruption reshapes the hematopoietic differentiation landscape
Mutations in genes involved in DNA methylation (DNAme; for example, TET2 and DNMT3A)
are frequently observed in hematological malignancies 1 , 2 – 3 and clonal hematopoiesis 4 …
are frequently observed in hematological malignancies 1 , 2 – 3 and clonal hematopoiesis 4 …
Hepatic stellate cell transdifferentiation involves genome-wide remodeling of the DNA methylation landscape
A Page, P Paoli, EM Salvador, S White, J French… - Journal of …, 2016 - Elsevier
… The aim of this study is to investigate the role of DNA methylation/hydroxymethylation in …
via DNA methylation or via some indirect mode of action. We firstly compared DNA methylation …
via DNA methylation or via some indirect mode of action. We firstly compared DNA methylation …