The power and the promise of DNA methylation markers

PW Laird - Nature Reviews Cancer, 2003 - nature.com
Marker discovery. How do we identify the DNA methylation markers that will be of greatest
clinical use among the tens of millions of CpG dinucleotides and tens of thousands of gene-…

DNA methylation markers in colorectal cancer

MS Kim, J Lee, D Sidransky - Cancer and Metastasis Reviews, 2010 - Springer
DNA methylation patterns may also be predictors of metastatic or aggressive … DNA methylation
as a driving force in colorectal neoplasia and its emerging value as a molecular marker in …

DNA methylation as a marker for the past and future

T Ushijima, T Nakajima, T Maekita - Journal of gastroenterology, 2006 - Springer
… The use of aberrant methylation as a marker is likely to be expanded to the detection of past
… by promoter methylation and the expanding use of DNA methylation as a marker, enabling …

DNA methylation markers for diagnosis and prognosis of common cancers

X Hao, H Luo, M Krawczyk, W Wei… - Proceedings of the …, 2017 - National Acad Sciences
methylation data from The Cancer Genome Atlas (TCGA) and machine learning methods, we
evaluated the utility of DNA methylation … We identified cancer markers in a training cohort of …

Principles of DNA methylation and their implications for biology and medicine

Y Dor, H Cedar - The Lancet, 2018 - thelancet.com
… This DNA methylation paradigm is a key player in medicine. Some changes in methylation
closely correlate with age providing a marker for biological ageing, and these same sites …

Identification of novel DNA methylation markers in cervical cancer

HC Lai, YW Lin, THM Huang, P Yan… - … journal of cancer, 2008 - Wiley Online Library
… cancers, DNA methylation could serve as a marker for early … DNA methylation may be useful
as a marker for cervical cancer screening.12, 17 Most previous studies of DNA methylation

Epigenetic diagnostics of cancer—the application of DNA methylation markers

J Paluszczak, W Baer-Dubowska - Journal of applied genetics, 2006 - Springer
markers are especially needed. The review describes the diagnostic potential of DNA
methylation markers… Examples of potential cancer DNA methylation markers are listed in Table 1. …

[HTML][HTML] Utility of DNA methylation markers for diagnosing cancer

SA Qureshi, MU Bashir, A Yaqinuddin - International Journal of Surgery, 2010 - Elsevier
… was used as a DNA methylation marker.22, 23, 24 DNA methylation markers that are specific
for … Until such cancer-specific DNA methylation markers are found, studies have shown that …

[HTML][HTML] Prognostic DNA methylation markers for prostate cancer

SH Strand, TF Orntoft, KD Sorensen - International journal of molecular …, 2014 - mdpi.com
… promising potential for DNA methylation markers in relation … This review focuses on the utility
of DNA methylation markers … “Biological markers”, “Prostatic Neoplasms”, “DNA Methylation”…

DNA methylation markers and early recurrence in stage I lung cancer

MV Brock, CM Hooker, E Ota-Machida… - … England Journal of …, 2008 - Mass Medical Soc
… cancer and are frequently methylated in lung cancer. We hypothesized that the
methylation-specific PCR assay could be used to define patterns of DNA methylation that can …