[引用][C] The essentials of DNA methylation

A Bird - cell, 1992 - Elsevier
… Several proteins that bind to methylated DNA are known. Two of these, MeCPl and MeCP2
(for methylCpG-binding proteins), can bind to base-paired methylCpG in any sequence …

DNA methylation and gene expression

Z Siegfried, I Simon - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
… First, methylated cytosines can inhibit the binding of some transcription factors with their …
, methylated CpGs can affect chromatin states through the recruitment of methyl CpG binding …

Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

N Fujita, S Watanabe, T Ichimura, S Tsuruzoe… - Journal of Biological …, 2003 - ASBMB
… In this study, we show that H3 (Lys-9) methylase Suv39h1 and the methyl lysine-binding …
to methylated DNA regions. We discuss the possible pathway from DNA methylation to the …

The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing

Z Lang, M Lei, X Wang, K Tang, D Miki, H Zhang… - Molecular cell, 2015 - cell.com
DNA methylation is a conserved epigenetic mark that plays … Methyl-CpG-binding domain
(MBD) proteins are important interpreters of DNA methylation that recognize methylated CG …

New concepts in DNA methylation

A Jeltsch, RZ Jurkowska - Trends in biochemical sciences, 2014 - cell.com
DNA methylation in a greater depth. Second, we present a modified stochastic DNA methylation
… de novo and the maintenance methylation process at CpG and non-CpG sites. Finally, …

Intrathecal 5-azacytidine inhibits global DNA methylation and methyl-CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic …

Y Wang, C Liu, QL Guo, JQ Yan, XY Zhu, CS Huang… - Brain research, 2011 - Elsevier
… To determine how changes in global DNA methylation and MeCP2 … DNA methylation affects
these changes and attenuates neuropathic pain, we used intrathecal 5-azacytidine, a DNA

Genomic DNA methylation: the mark and its mediators

RJ Klose, AP Bird - Trends in biochemical sciences, 2006 - cell.com
… by which DNA methylation is targeted to specific regions of the genome and interpreted by
methyl-CpG-binding proteins. Recent studies have illuminated the role of DNA methylation in …

Biological functions of methyl-CpG-binding proteins

PA Defossez, I Stancheva - Progress in molecular biology and translational …, 2011 - Elsevier
CpG dinucleotides, while in plants DNA methylation can be found at CpG as well as non-CpG
be globally methylated with the exception of stretches of DNA 500–2000 bp long known as …

DNA methylation and chromatin structure: the puzzling CpG islands

P Caiafa, M Zampieri - Journal of cellular biochemistry, 2005 - Wiley Online Library
… termed CpG islands because they are particularly rich in this dinucleotide, which is the best
substrate for enzymes involved in DNA methylation. Anomalous insertion of methyl groups in …

DNA methylation and cancer

RL Momparler, V Bovenzi - Journal of cellular physiology, 2000 - Wiley Online Library
… Another class of methylated CpG-binding proteins (MeCPs) … to bind DNA containing highly
methylated CpG dinucleotides. … 12 methylCpGs for preferential binding to methylated DNA