Temporal Modulation of DNA Methylation and Gene Expression in Monolayer and 3D Spheroids of Dental Pulp Stem Cells during Osteogenic Differentiation: A …

S Raik, R Thakur, V Rattan, N Kumar, A Pal… - Tissue Engineering and …, 2022 - Springer
… osteogenic differentiation through the modulation of DNA methylation in MSCs are sparse
… This can be attributed to our observation of increase expression of methylation modulators (…

Methyl benzoate and cinnamate analogs as modulators of DNA methylation in hepatocellular carcinoma

D Castro‐Vazquez… - Chemical Biology & …, 2022 - Wiley Online Library
DNA methylation inhibition. The molecular docking of 21 and 14 suggested that they partly
bind to the SAH-binding pocket of DNA … sources of DNA methylation modulating agents. …

Modulation of DNA methylation levels sensitizes doxorubicin-resistant breast adenocarcinoma cells to radiation-induced apoptosis

L Luzhna, O Kovalchuk - Biochemical and biophysical research …, 2010 - Elsevier
… the status of DNA methylation in MCF-7 and MCF-7/DOX cells. The cytosine extension assay
revealed that MCF-7/DOX cells had significantly lower levels of methylated CCGG sites as …

[HTML][HTML] DNA methylation targeting: the DNMT/HMT crosstalk challenge

O Castillo-Aguilera, P Depreux, L Halby, PB Arimondo… - Biomolecules, 2017 - mdpi.com
… by epigenetic modulators that are active on either the DNA or … methylating hemimethylated
DNA and thus DNA methylationDNA methylation, but they can also participate in methylation

Exploration of cell cycle regulation and modulation of the DNA methylation mechanism of pelargonidin: Insights from the molecular modeling approach

N Karthi, A Karthiga, T Kalaiyarasu, A Stalin… - … Biology and Chemistry, 2017 - Elsevier
… with epigenetic signals related to DNA methylation. DNA methylation is an epigenetic signal
… show pelargonidin to be a novel inhibitor of cell division and of DNA methylation regulators. …

[HTML][HTML] Methylenetetrahydrofolate dehydrogenase 1 silencing expedites the apoptosis of non-small cell lung cancer cells via modulating DNA methylation

K Ding, J Jiang, L Chen, X Xu - Medical Science Monitor …, 2018 - ncbi.nlm.nih.gov
DNA methylation is one of … , DNA methylation refers to a reaction of methylation of fifth carbon
atoms of cytosine nucleotides (C) to 5 methyl cytosine (5′-mC) under the catalysis of DNA

Common non-epigenetic drugs as epigenetic modulators

J Lötsch, G Schneider, D Reker, MJ Parnham… - Trends in molecular …, 2013 - cell.com
… may induce alterations in DNA methylation patterns or histone conformations. These effects
occur via chemical structural interactions with epigenetic enzymes, through interactions with …

[HTML][HTML] ZCCHC13-mediated induction of human liver cancer is associated with the modulation of DNA methylation and the AKT/ERK signaling pathway

Z Li, Z Li, L Wang, C Long, Z Zheng… - Journal of translational …, 2019 - Springer
DNA methylation was measured by methylation-specific PCR and bisulfite sequencing.
The role of ZCCHC13 methylation was further evaluated using the demethylating agent, 5-aza-2…

[HTML][HTML] Aryl hydrocarbon receptor as a DNA methylation reader in the stress response pathway

W Habano, T Miura, J Terashima, S Ozawa - Toxicology, 2022 - Elsevier
DNA methylation reader, unlike classical methylation readers, such as methyl-CpG-binding
protein 2, which binds to methylated … stresses by modulating DNA methylation. Thus, the …

Modulation of DNA methylation and gene expression in cultured sycamore cells treated by hypomethylating base analog

J Ngernprasirtsiri, T Akazawa - European journal of …, 1990 - Wiley Online Library
… Indeed, the involvement of DNA methylation at the transcriptional level in plant gene … role
of DNA methylation in gene expression by experimentally manipulating DNA methylation levels …