… DNA methylation differences between patients and healthy controls across neurodegenerative
disorders… to test for association between each DNA methylation site and the traits. We …

… Neurological Disorders (UCL Institute of Neurology) and compare the levels of global DNA
methylation … elucidate whether global DNA methylation is involved in the pathogenesis of AD. …

… K assay and to specifically assess DNA methylation at a single base level. We choose
dosage-sensitive genes known to be involved in different neurological disorders, including APP (…

… The neurological disorder most intensely studied with regard to epigenetic changes is Rett
… show the putative DNA methylation changes that might occur in neurological disorders, such …

… Finally, based on the recent studies we conclude that DNA methylation status may have
implications in clinical diagnostics and therapeutics as a potential epigenetic biomarker of NPDs…

… In recent years, epigenetic modification of both DNA and histones such as DNA methylation
… that aberrant DNA methylation is closely associated with neurological disorders such as AD. …

… ranging from aging to neurological disorders. The DNA methylation status of genes is … ,
yet the part played by aberrant DNA methylation in homocysteine-related pathologies is …

… , sufficiently large patient cohorts, and adequate bioinformatic analysis methods, we will gain
more insights into the underlying mechanisms of neurological disorders in PD in the future. …

… neurological damage takes place. Here, we discuss the current evidence for DNA methylation
… intervention targeting DNA methylation modifications associated with this disorder. …

… Mutations in DNMT1 cause two adult-onset neurological disorders with autosomal dominant
… limit access to hemi-methylated DNA.14 In fact, DNMT1 is recruited to DNA by its obligate …