DNA methylation and its implications and accessibility for neuropsychiatric therapeutics

JJ Day, AJ Kennedy, JD Sweatt - Annual review of …, 2015 - annualreviews.org
DNA methylation processes. Overall, this has generated compelling reasons to believe that
DNA methylation … Thus, clinical stress disorders such as PTSD might be the first area wherein …

Mitochondrial DNA methylation and human diseases

A Stoccoro, F Coppedè - International Journal of Molecular Sciences, 2021 - mdpi.com
… in the DNA sequence, including DNA methylation, histone … cancer, as well as for neurological
and autoimmune diseases, and, … disorder and attention-deficit hyperactivity disorder when …

Epigenetic basis of lead-induced neurological disorders

T Wang, J Zhang, Y Xu - … journal of environmental research and public …, 2020 - mdpi.com
… Epigenetic changes associated with AD were observed in DNA methylation, histone
modifications and ncRNA. In a human postmortem case-control study, global DNA methylation was …

DNA methylation: basic biology and application to traumatic brain injury

BA Mateen, CS Hill, SC Biddie, DK Menon - Journal of neurotrauma, 2017 - liebertpub.com
… implicated in neurological disease pathogenesis, and 39 have been implicated in
neuropsychiatric disorders. The only other study directly examining DNA methylation following TBI …

A review of DNA methylation in depression

D Chen, L Meng, F Pei, Y Zheng, J Leng - Journal of Clinical Neuroscience, 2017 - Elsevier
… As one of the most common psychiatric disorders, depression … Recently, DNA methylation
has been regarded as a potential … DNA methylation and depression. The association between …

[HTML][HTML] DNA methylation and brain structure and function across the life course: A systematic review

ENW Wheater, DQ Stoye, SR Cox, JM Wardlaw… - Neuroscience & …, 2020 - Elsevier
DNA methylation may also occur after an initial change in gene expression and … neurological
phenotypes involve DNAm dysregulation. Rett syndrome is a severe neurological disorder

DNA methylation and hydroxymethylation and behavior

SR Rustad, LA Papale, RS Alisch - Behavioral Neurogenomics, 2019 - Springer
… Here, we review the recent links that indicate DNA methylation (… related to psychiatric disorders
and hold clinical relevance. … role for DNA methylation in eating disorder psychopathology. …

Defects of mutant DNMT1 are linked to a spectrum of neurological disorders

J Baets, X Duan, Y Wu, G Smith, WW Seeley… - Brain, 2015 - academic.oup.com
… only has deleterious impact on its DNA binding and critical interactions with … DNA methylation
of the newly synthesized DNA strand, as a significant portion of maintenance methylation

[HTML][HTML] Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels

S Horvath, P Langfelder, S Kwak, J Aaronson… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
disorders may be due to differences in polyglutamine protein context or functions because
these disorders … The Auckland samples were obtained from the Neurological Foundation of …

DNA methylation and adult neurogenesis

EM Jobe, X Zhao - Brain Plasticity, 2017 - content.iospress.com
… Mutations in MeCP2 are the cause of the neurodevelopmental disorder Rett syndrome (RTT),
but they are also associated with a number of other neurological disorders, including …