[HTML][HTML] Associations of serum DNA methylation levels of chemokine signaling pathway genes with mild cognitive impairment (MCI) and Alzheimer's disease (AD)
T Zou, X Zhou, Q Wang, Y Zhao, M Zhu, L Zhang… - Plos one, 2023 - journals.plos.org
… DNA methylation is a major component of epigenetics, which is influenced by environmental
factors leading to progression of diseases and providing new directions on pathogenesis …
factors leading to progression of diseases and providing new directions on pathogenesis …
DNA methylation level of the neprilysin promoter in Alzheimer's disease brains
… a pathological … DNA methylation status of CpG islands in the NEP promoter and its expression
level in AD brains. We performed pyrosequencing analyses to detect the DNA methylation …
level in AD brains. We performed pyrosequencing analyses to detect the DNA methylation …
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer's dementia: a network Mendelian randomization analysis
D Liu, Y Wang, H Jing, Q Meng, J Yang - Epigenetics, 2022 - Taylor & Francis
… underlying the pathogenesis of Alzheimer’s dementia. Our findings shed light on the role
of DNA methylation in gene expression and in the development of Alzheimer’s dementia. …
of DNA methylation in gene expression and in the development of Alzheimer’s dementia. …
Epigenetics in Alzheimer's disease: a focus on DNA modifications
N Coppieters, M Dragunow - Current pharmaceutical design, 2011 - ingentaconnect.com
… the etiology of the disease. In this review we focus on discussing the roles of DNA methylation
and … for identifying changes in DNA modifications that are specific for AD pathology. In this …
and … for identifying changes in DNA modifications that are specific for AD pathology. In this …
Epigenetic dysregulation in Alzheimer's disease: cause or consequence?
… , represent critical factors in the pathogenesis of AD (eg, [… that DNA methylation patterns
associated with brain disorders … being able to use blood DNA methylation signatures for accurate …
associated with brain disorders … being able to use blood DNA methylation signatures for accurate …
Prediction of Alzheimer's disease based on deep neural network by integrating gene expression and DNA methylation dataset
… We present a novel Alzheimer's disease prediction model … the association between gene
expression and DNA methylation. … gene expression and DNA methylation and found that it can …
expression and DNA methylation. … gene expression and DNA methylation and found that it can …
Whole genome methylation sequencing in blood identifies extensive differential DNA methylation in late‐onset dementia due to Alzheimer's disease
C Breen, LA Papale, LR Clark… - Alzheimer's & …, 2024 - Wiley Online Library
… levels alone cannot suffice to conclusively test for mechanisms of AD pathophysiology, our
data provide an essential substrate for future combined methylomic, genomic, transcriptomic, …
data provide an essential substrate for future combined methylomic, genomic, transcriptomic, …
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies
… the diagnosis of Alzheimer's disease. A primer for practicing … with pathological AD (Yu et
al., 2014a). We and others have also detected DNA methylation associations with AD pathology …
al., 2014a). We and others have also detected DNA methylation associations with AD pathology …
DNA methylation and tag SNPs of the BDNF gene in conversion of amnestic mild cognitive impairment into Alzheimer's disease: a cross-sectional cohort study
B Xie, Z Liu, W Liu, L Jiang, R Zhang… - … of Alzheimer's …, 2017 - content.iospress.com
… , aberrant DNA methylation at BDNF gene has not been well demonstrated in the pathogenesis
of … This study will help to understand the pathogenesis of AD progression, and provide …
of … This study will help to understand the pathogenesis of AD progression, and provide …
Psychosis-associated DNA methylomic variation in Alzheimer's disease cortex
… This study used epigenome-wide association study (EWAS) Illumina 450K DNA methylation
data that had already been generated in human postmortem brain tissue from donors in the …
data that had already been generated in human postmortem brain tissue from donors in the …