… The recent advances in the field had a significant impact on our understanding of the role
of DNA methylation in mammals, the enzymatic machineries involved in its regulation and its …

… Binary vectors P i , Q i and D i , where i = 1, 2, denote methylation patterns on a … DNA
methylation patterns to estimate the rates at which failure of maintenance and de novo methylation …

… -acquisition of DNA methylation drastically affected allelic histone methylation patterns,
providing the first evidence for a mechanistic link between DNA and histone methylation at ICRs. …

… Although extensive in plants and mammals, the absence of detectable DNA methylation
in some eukaryotes such as Drosophila2 and Saccharomyces cerevisiae3 has raised doubts …

… Lethality in the absence of DNMT enzymes supports the notion that DNA methylation is
essential for mammalian development. However, the actual cause of embryonic lethality remains …

… regulates de novo DNA methylation in mammals and has … methyltransferases found in these
organisms, mammalian DNA … Rather, specific genomic methylation patterns in mammals are …

… As we have discussed, complex mechanisms have evolved in mammals to ensure that
DNA methylation patterns are faithfully reproduced through cell generations. Among the key …

… ], UHRF1 may cooperate with DNMT3A for the establishment of methylation patterns. Despite
the involvement of UHRF1 in de novo DNA methylation in oocytes, our group found that the …

… This could be the explanation of the fact that when we consider mammals of 30C or 37C
we do not observe huge differences in DNA methylation and other factors must be taken into …

… In mammalian development, epigenetic modifications, including DNA methylation patterns,
… At two points in the life cycle, DNA methylation marks are reprogrammed on a global scale, …