DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… The two waves of DNA methylation reprogramming involve both distinct and shared … the
key reprogramming events, focusing on the important players in these processes, including DNA …
key reprogramming events, focusing on the important players in these processes, including DNA …
DNA methylation and cellular reprogramming
DD De Carvalho, JS You, PA Jones - Trends in cell biology, 2010 - cell.com
… emphasis on DNA methylation during cellular reprogramming. Recent data suggest that
DNA methylation is a major barrier to induced pluripotent stem (iPS) cell reprogramming. The …
DNA methylation is a major barrier to induced pluripotent stem (iPS) cell reprogramming. The …
DNA methylation reprogramming in the germ line
DJ Lees-Murdock, CP Walsh - Epigenetics, 2008 - Taylor & Francis
… Reprogramming methylation in the primordial germ cells … In addition to direct transcriptional
silencing, DNA methylation … and extent of DNA methylation reprogramming of many different …
silencing, DNA methylation … and extent of DNA methylation reprogramming of many different …
Dynamic reprogramming of DNA methylation in the early mouse embryo
… De novo methylation was observed specifically in the inner cell mass (ICM) … reprogramming
cycle during preimplantation development. The three phases of methylation reprogramming …
cycle during preimplantation development. The three phases of methylation reprogramming …
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Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
J Deng, R Shoemaker, B Xie, A Gore… - Nature …, 2009 - nature.com
… Consistent with these reports, we did not observe widespread changes of DNA methylation
during reprogramming in the CpG islands on chromosomes 12 and 20. Surprisingly, we still …
during reprogramming in the CpG islands on chromosomes 12 and 20. Surprisingly, we still …
Epigenetic reprogramming of cancer cells via targeted DNA methylation
AG Rivenbark, S Stolzenburg, AS Beltran, X Yuan… - Epigenetics, 2012 - Taylor & Francis
… Cells transduced with ZF-97 SKD did not exhibit targeted DNA methylation (Fig. S1). To
determine if we could directionally target DNA methylation, we positioned the DNMT3a domain …
determine if we could directionally target DNA methylation, we positioned the DNMT3a domain …
Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers
… methylation erasure from the zygote. Deamination by AID, BER and passive demethylation
have been implicated in reprogramming … the dynamics of DNA methylation reprogramming in …
have been implicated in reprogramming … the dynamics of DNA methylation reprogramming in …
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
… Genome-wide DNA methylation reprogramming occurs in … Global loss of methylation takes
place during PGC expansion … network, suggesting that reprogramming and pluripotency are …
place during PGC expansion … network, suggesting that reprogramming and pluripotency are …
Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo
… Our findings suggest a complex interplay between possible mechanisms of DNA methylation
reprogramming (that is, demethylation and de novo methylation) and DNA methylation …
reprogramming (that is, demethylation and de novo methylation) and DNA methylation …
Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer
N Beaujean, J Taylor, J Gardner, I Wilmut… - Biology of …, 2004 - academic.oup.com
… of methylated DNA is abnormal in a high proportion. By correlating DNA methylation with …
that do not undergo rapid reorganization of their DNA before the first mitosis fail to develop …
that do not undergo rapid reorganization of their DNA before the first mitosis fail to develop …