DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… As the epiblast rapidly adopts somatic epigenetic features after implantation, the DNA
methylation levels and patterns of the embryonic ectoderm in the E6.5 mouse embryo are more …
methylation levels and patterns of the embryonic ectoderm in the E6.5 mouse embryo are more …
[HTML][HTML] DNA methylation reprogramming of functional elements during mammalian embryonic development
… methylation reprogramming of enhancers may facilitate the temporal control of embryonic …
Our data suggest that DNA methylation reprogramming plays important roles in mammalian …
Our data suggest that DNA methylation reprogramming plays important roles in mammalian …
[HTML][HTML] DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… of the embryonic methylation pattern. The two waves of DNA methylation reprogramming …
In this review article, we provide an overview of the key reprogramming events, focusing on …
In this review article, we provide an overview of the key reprogramming events, focusing on …
[HTML][HTML] Conceptual links between DNA methylation reprogramming in the early embryo and primordial germ cells
… demethylation dynamics during epigenetic reprogramming. In addition, … DNA methylation
erasure in the early embryo and PGCs, further adding to our mechanistic understanding of DNA …
erasure in the early embryo and PGCs, further adding to our mechanistic understanding of DNA …
Dynamic reprogramming of DNA methylation in the early mouse embryo
… In this study, we have provided the first complete description of the cycle of methylation
reprogramming in mouse preimplantation embryos. This cycle is initiated shortly after sperm …
reprogramming in mouse preimplantation embryos. This cycle is initiated shortly after sperm …
[HTML][HTML] Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo
… between possible mechanisms of DNA methylation reprogramming (that is, demethylation
and de novo methylation) and DNA methylation maintenance in the early mouse embryo. …
and de novo methylation) and DNA methylation maintenance in the early mouse embryo. …
Germline-derived DNA methylation and early embryo epigenetic reprogramming: the selected survival of imprints
D Monk - The international journal of biochemistry & cell biology, 2015 - Elsevier
… post-fertilization reprograming to ensure a totipotent state necessary for embryonic
development. Although much of our knowledge of epigenetic reprogramming in embryos and germ …
development. Although much of our knowledge of epigenetic reprogramming in embryos and germ …
[HTML][HTML] DNA methylation, environmental exposures and early embryo development
M Breton-Larrivée, E Elder, S McGraw - Animal reproduction, 2019 - SciELO Brasil
… changes in DNA methylation can occur as a … of embryonic development. In this review, we
depict the mechanisms behind the embryonic epigenetic reprogramming of DNA methylation …
depict the mechanisms behind the embryonic epigenetic reprogramming of DNA methylation …
Methylation dynamics in the early mammalian embryo: implications of genome reprogramming defects for development
T Haaf - DNA methylation: development, genetic disease and …, 2006 - Springer
… If genome-wide methylation reprogramming in the early embryo is fundamental to the
formation of totipotent embryonic cells, one would expect that the preimplantation methylation …
formation of totipotent embryonic cells, one would expect that the preimplantation methylation …
DNA methylation reprogramming in the germ line
DJ Lees-Murdock, CP Walsh - Epigenetics, 2008 - Taylor & Francis
… Early studies of DNA methylation changes in the early embryo suggested a … embryo (ref.
3). These studies and those utilizing methylated cytosine antibodies, indicate that bulk DNA is …
3). These studies and those utilizing methylated cytosine antibodies, indicate that bulk DNA is …
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