DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… As the epiblast rapidly adopts somatic epigenetic features after implantation, the DNA
methylation levels and patterns of the embryonic ectoderm in the E6.5 mouse embryo are more …

[HTML][HTML] DNA methylation reprogramming of functional elements during mammalian embryonic development

C Li, Y Fan, G Li, X Xu, J Duan, R Li, X Kang, X Ma… - Cell discovery, 2018 - nature.com
methylation reprogramming of enhancers may facilitate the temporal control of embryonic
Our data suggest that DNA methylation reprogramming plays important roles in mammalian …

[HTML][HTML] DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
… of the embryonic methylation pattern. The two waves of DNA methylation reprogramming
In this review article, we provide an overview of the key reprogramming events, focusing on …

[HTML][HTML] Conceptual links between DNA methylation reprogramming in the early embryo and primordial germ cells

S Seisenberger, JR Peat, W Reik - Current opinion in cell biology, 2013 - Elsevier
… demethylation dynamics during epigenetic reprogramming. In addition, … DNA methylation
erasure in the early embryo and PGCs, further adding to our mechanistic understanding of DNA

Dynamic reprogramming of DNA methylation in the early mouse embryo

F Santos, B Hendrich, W Reik, W Dean - Developmental biology, 2002 - Elsevier
… In this study, we have provided the first complete description of the cycle of methylation
reprogramming in mouse preimplantation embryos. This cycle is initiated shortly after sperm …

[HTML][HTML] Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

J Arand, M Wossidlo, K Lepikhov, JR Peat, W Reik… - Epigenetics & …, 2015 - Springer
… between possible mechanisms of DNA methylation reprogramming (that is, demethylation
and de novo methylation) and DNA methylation maintenance in the early mouse embryo. …

Germline-derived DNA methylation and early embryo epigenetic reprogramming: the selected survival of imprints

D Monk - The international journal of biochemistry & cell biology, 2015 - Elsevier
… post-fertilization reprograming to ensure a totipotent state necessary for embryonic
development. Although much of our knowledge of epigenetic reprogramming in embryos and germ …

[HTML][HTML] DNA methylation, environmental exposures and early embryo development

M Breton-Larrivée, E Elder, S McGraw - Animal reproduction, 2019 - SciELO Brasil
… changes in DNA methylation can occur as a … of embryonic development. In this review, we
depict the mechanisms behind the embryonic epigenetic reprogramming of DNA methylation

Methylation dynamics in the early mammalian embryo: implications of genome reprogramming defects for development

T Haaf - DNA methylation: development, genetic disease and …, 2006 - Springer
… If genome-wide methylation reprogramming in the early embryo is fundamental to the
formation of totipotent embryonic cells, one would expect that the preimplantation methylation

DNA methylation reprogramming in the germ line

DJ Lees-Murdock, CP Walsh - Epigenetics, 2008 - Taylor & Francis
… Early studies of DNA methylation changes in the early embryo suggested a … embryo (ref.
3). These studies and those utilizing methylated cytosine antibodies, indicate that bulk DNA is …