Dynamic reprogramming of DNA methylation in the early mouse embryo
… cycle of methylation reprogramming in mouse preimplantation … chromatin remodelling in the
mouse zygote. Using a sensitive … for the active demethylation observed in the mouse zygote. …
mouse zygote. Using a sensitive … for the active demethylation observed in the mouse zygote. …
[PDF][PDF] DNA methylation reprograming and DNA repair in the mouse zygote
K Lepikhov, M Wossidlo, J Arand… - International Journal of …, 2010 - academia.edu
… We and other research groups have shown that in late G1 mouse zygotes, during phase
of active DNA demethylation, DNA strand breaks can be detected in the paternal pronucleus …
of active DNA demethylation, DNA strand breaks can be detected in the paternal pronucleus …
DNA methylation reprogramming during mammalian development
Y Zeng, T Chen - Genes, 2019 - mdpi.com
… Removal of ZFP57 from the mouse zygote results in embryonic and neonatal lethality due
to defects in the maintenance of both maternal and paternal imprints at multiple imprinted loci […
to defects in the maintenance of both maternal and paternal imprints at multiple imprinted loci […
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
CR Farthing, G Ficz, RK Ng, CF Chan, S Andrews… - PLoS …, 2008 - journals.plos.org
… Indeed, we confirmed by bisulphite sequencing that whilst the promoter of Nanog was
completely methylated in sperm, it was demethylated in the zygote to an overall extent that …
completely methylated in sperm, it was demethylated in the zygote to an overall extent that …
Epigenetic reprogramming of the zygote in mice and men: on your marks, get set, go!
R Fraser, CJ Lin - Reproduction, 2016 - rep.bioscientifica.com
… A recent study investigating the histone modifications that may be implicated in promoting
or inhibiting DNA methylation in oocytes, showed that CGIs destined for DNA methylation had …
or inhibiting DNA methylation in oocytes, showed that CGIs destined for DNA methylation had …
Germline-derived DNA methylation and early embryo epigenetic reprogramming: the selected survival of imprints
D Monk - The international journal of biochemistry & cell biology, 2015 - Elsevier
… , there is a second wave of global epigenetic reprograming that is critical for the establishment
of totipotency. In mouse the zygote undergoes massive genome-wide demethylation, with …
of totipotency. In mouse the zygote undergoes massive genome-wide demethylation, with …
Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes
JS Park, YS Jeong, ST Shin, KK Lee… - … dynamics: an official …, 2007 - Wiley Online Library
… patterns in bovine zygotes. We report a third type of early methylation reprogramming that
is different from those of the mouse and the sheep. Immunocytochemical inspection of bovine …
is different from those of the mouse and the sheep. Immunocytochemical inspection of bovine …
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos
DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… Conflicting observations made by IF analysis in zygotes and DNA sequencing after BSC
created a conundrum regarding DNA demethylation and reprogramming. While the loss of 5mC …
created a conundrum regarding DNA demethylation and reprogramming. While the loss of 5mC …
Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo
… of DNA methylation reprogramming (that is, demethylation and de novo methylation) and DNA
methylation … in DNA methylation (5mC and 5hmC) in the zygote are mainly dependent on …
methylation … in DNA methylation (5mC and 5hmC) in the zygote are mainly dependent on …
DNA methylation and cellular reprogramming
DD De Carvalho, JS You, PA Jones - Trends in cell biology, 2010 - cell.com
… emphasis on DNA methylation during cellular reprogramming. Recent data suggest that
DNA methylation is a major barrier to induced pluripotent stem (iPS) cell reprogramming. The …
DNA methylation is a major barrier to induced pluripotent stem (iPS) cell reprogramming. The …
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