… cycle of methylation reprogramming in mouse preimplantation … chromatin remodelling in the
mouse zygote. Using a sensitive … for the active demethylation observed in the mouse zygote. …

… We and other research groups have shown that in late G1 mouse zygotes, during phase
of active DNA demethylation, DNA strand breaks can be detected in the paternal pronucleus …

… Removal of ZFP57 from the mouse zygote results in embryonic and neonatal lethality due
to defects in the maintenance of both maternal and paternal imprints at multiple imprinted loci […

… Indeed, we confirmed by bisulphite sequencing that whilst the promoter of Nanog was
completely methylated in sperm, it was demethylated in the zygote to an overall extent that …

… A recent study investigating the histone modifications that may be implicated in promoting
or inhibiting DNA methylation in oocytes, showed that CGIs destined for DNA methylation had …

… , there is a second wave of global epigenetic reprograming that is critical for the establishment
of totipotency. In mouse the zygote undergoes massive genome-wide demethylation, with …

… patterns in bovine zygotes. We report a third type of early methylation reprogramming that
is different from those of the mouse and the sheep. Immunocytochemical inspection of bovine …

… Conflicting observations made by IF analysis in zygotes and DNA sequencing after BSC
created a conundrum regarding DNA demethylation and reprogramming. While the loss of 5mC …

… of DNA methylation reprogramming (that is, demethylation and de novo methylation) and DNA
methylation … in DNA methylation (5mC and 5hmC) in the zygote are mainly dependent on …

… emphasis on DNA methylation during cellular reprogramming. Recent data suggest that
DNA methylation is a major barrier to induced pluripotent stem (iPS) cell reprogramming. The …