[HTML][HTML] Optimized screening of DNA methylation sites combined with gene expression analysis to identify diagnostic markers of colorectal cancer
Z Ye, G Song, J Liang, S Yi, Y Gao, H Jiang - BMC cancer, 2023 - Springer
Background The prognosis of patients with colorectal cancer is related to early detection.
However, commonly used screening markers lack sensitivity and specificity. In this study, we …
However, commonly used screening markers lack sensitivity and specificity. In this study, we …
Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation
… of DNA methylation-related biological events. In this study, the implementation of virtual
screening … DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. …
screening … DNA methylation in vitro and disrupts DNMT1/UHRF1 interactions at a cellular level. …
Review of blood-based colorectal cancer screening: how far are circulating cell-free DNA methylation markers from clinical implementation?
MBW Ørntoft - Clinical colorectal cancer, 2018 - Elsevier
… CRC screening marker … DNA methylation marker candidates for CRC screening. On the
basis of a methodical literature search, the past, present, and future of cell-free DNA screening …
basis of a methodical literature search, the past, present, and future of cell-free DNA screening …
[HTML][HTML] Virtues and weaknesses of DNA methylation as a test for cervical cancer prevention
AT Lorincz - Acta cytologica, 2016 - karger.com
… There have been relatively few validation studies of DNA methylation biomarkers in large
population-based screening studies, but an encouraging development more recently is the …
population-based screening studies, but an encouraging development more recently is the …
Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancer
… DNA methylation testing of host genes in cytological specimens, offer promise as an objective
biomarker for cervical cancer screening … have identified increased DNA methylation of host …
biomarker for cervical cancer screening … have identified increased DNA methylation of host …
DNA methylation analysis for screening and diagnostic testing in neurodevelopmental disorders
… DNA methylation is the process where methyl groups are added to DNA molecules which
changes the activity of the DNA … DNA methylation in cancer, the role of DNA methylation in the …
changes the activity of the DNA … DNA methylation in cancer, the role of DNA methylation in the …
Current methylation screening methods
TK Wojdacz - Epigenomics, 2009 - Taylor & Francis
… DNA methylation is the covalent addition of a methyl group to the cytosines … of DNA methylation
and genetics have occurred at the same time. However, for years, the field of methylation …
and genetics have occurred at the same time. However, for years, the field of methylation …
[HTML][HTML] Analysis of DNA methylation status in bodily fluids for early detection of cancer
K Yokoi, K Yamashita, M Watanabe - International journal of molecular …, 2017 - mdpi.com
… studies that analyzed DNA methylation in bodily fluids as a less-invasive cancer
screening. … In this article, we reviewed studies that analyzed DNA methylation in less-invasively-…
screening. … In this article, we reviewed studies that analyzed DNA methylation in less-invasively-…
Detection of fecal DNA methylation for colorectal neoplasia: does it lead to an optimal screening test?
T Nagasaka, A Goel, N Matsubara… - Acta medica …, 2006 - ousar.lib.okayama-u.ac.jp
… To test the validity and usefulness of fecal-based epigenetic marker screening, human
colorectal cancer has provided a good model for investigating whether DNA methylation can be …
colorectal cancer has provided a good model for investigating whether DNA methylation can be …
[HTML][HTML] Efficacy of cell-free DNA methylation-based blood test for colorectal cancer screening in high-risk population: a prospective cohort study
F Zhao, P Bai, J Xu, Z Li, S Muhammad, D Li, Z Zhang… - Molecular Cancer, 2023 - Springer
… To establish the utility of our methylation screening model, we compared it to conventional
serum biomarkers that have been used for the detection of CRC – serum carcinoembryonic …
serum biomarkers that have been used for the detection of CRC – serum carcinoembryonic …