… To discover novel compounds for the inhibition of human DNA methyltransferases, we
have screened a set of small molecules available from the NCI database. Using a 3-dimensional …

… Availability of a blood-based test for colorectal cancer is expected to improve screening …
DNA methylation as a technically robust and biologically relevant indicator. DNA methylation is …

… Aberrant DNA methylation in selected gene promoters has emerged as a new epigenetic …
CRC screening is the most efficient strategy to reduce death. Specific DNA methylation events …

… of a new type of biomarker, DNA methylation, which is of great … including genome-wide
screening methods as well as locus- … In some cases, DNA methylation based biomarkers have …

… In humans, aberrant DNA methylation is associated with several malignancies, … DNA
methylation and present the use of methylation biomarkers in laboratory medicine. DNA methylation …

… the analysis of DNA methylation would significantly expand … This study describes a
high-throughput quantitative methylation … technology for mutation screening and expression …

… The development of noninvasive screening tests is important to reduce mortality from
gastrointestinal neoplasia. We sought to develop such a test by analysis of DNA methylation from …

… systems and offers the opportunity for high-throughput screening, as many single cells can
be screened in parallel. In addition to this study, critical principles and caveats of single cell …

… Thus, the prerequisite for using aberrant DNA methylation in screening seems to be there.
Recent data suggest that the most OC tumors originate from precursor lesions in the fimbrial …

… screening for changes in DNA methylation at CpG dinucleotides—a global epigenetic marker
involved in gene activity regulation. DNA methylation … of DNA-methylation biomarkers to …