[HTML][HTML] Quantification method of ctDNA using cell-free DNA methylation profile for noninvasive screening and monitoring of colon cancer

H Ryu, JH Kim, YJ Kim, H Jeon, BC Kim, Y Jeon… - Clinical …, 2024 - Springer
… the amount of circulating tumor DNA (ctDNA) in the blood samples of these same patients,
utilizing cell-free DNA methylation profiles. Notably, the methylation profiles of ctDNA in the …

[HTML][HTML] Opportunities for early cancer detection: the rise of ctDNA methylation-based pan-cancer screening technologies

N Constantin, AAI Sina, D Korbie, M Trau - Epigenomes, 2022 - mdpi.com
screening for changes in DNA methylation at CpG dinucleotides—a global epigenetic marker
involved in gene activity regulation. DNA methylation … of DNA-methylation biomarkers to …

Methods in DNA methylation profiling

T Zuo, B Tycko, TM Liu, HJL Lin, THM Huang - Epigenomics, 2009 - Taylor & Francis
Metastable and somatically heritable patterns of DNA methylation provide an important
level of genomic regulation. In this article, we review methods for analyzing these genome-wide …

[HTML][HTML] Identifying CpG sites associated with eczema via random forest screening of epigenome-scale DNA methylation

BM Quraishi, H Zhang, TM Everson, M Ray… - Clinical …, 2015 - Springer
… to revise DNA methylation. This is supported by our comparison of DNA methylation between
the … Hence, there is a need to further examine potential associations of DNA methylation of …

Techniques used in studies of age‐related DNA methylation changes

TK Wojdacz, LL Hansen - Annals of the New York Academy of …, 2006 - Wiley Online Library
methylation content and the methylation status of specific loci. The majority of methylation
screening protocols utilizes methylation-… All methods either examine only one specific DNA

DNA methylation marker for the triage of hrHPV positive women in cervical cancer screening: Real-world evidence in Taiwan

CL Chang, SC Ho, YF Su, YC Juan, CY Huang… - Gynecologic …, 2021 - Elsevier
methylation (PAX1 m ) test as a triage tool for hrHPV+ women in a real-world cervical cancer
screening … Pap smear and hrHPV DNA testing separately for primary screening in this study …

DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population

N Li, Y Hu, X Zhang, Y Liu, Y He… - … journal of cancer, 2021 - Wiley Online Library
… Objective strategies are required in cervical cancer screening. We have identified several
DNA methylation markers with high sensitivity and specificity to detect cervical intraepithelial …

A rapid screening system evaluates novel inhibitors of DNA methylation and suggests F-box proteins as potential therapeutic targets for high-risk neuroblastoma

L Penter, B Maier, U Frede, B Hackner, T Carell… - Targeted …, 2015 - Springer
… with DNA methylation patterns remains valid, the identification of new inhibitors of DNA
Several novel inhibitors of DNA methyltransferases have been identified, which to our …

Strategies for validation and testing of DNA methylation biomarkers

C Noehammer, W Pulverer, MR Hassler, M Hofner… - …, 2014 - Taylor & Francis
… We further show in the present review sample-size calculations for genome-wide methylation
screening studies which, independent from which platform technology is used, reveal that …

Identification and validation of a 3-gene methylation classifier for HPV-based cervical screening on self-samples

W Verlaat, BC Snoek, DAM Heideman, SM Wilting… - Clinical Cancer …, 2018 - AACR
… to increase the coverage in cervical screening programs. Molecular triage directly on hrHPV-…
full molecular cervical screening. Here, we set out to identify a DNA methylation classifier for …