… of the promoter region to examine DNA methylation is a critical step that should be carefully
considered in the development of DNA methylation markers for cancer screening. This is …

… DNA methylation is largely restricted to cytosine residues within the 5-CpG dinucleotides of
certain genes. DNA methylation … of DNA methylation in the context of abnormally methylated …

… In this study, we investigated DNA methylation characteristics and screened potential
epigenetic markers. We identified several key genes, such as IRS1, KLF5, CYP1B1, ETS1, and …

… CRC screening has proven efficient for early detection of cancerous lesions, but current
screening strategies suffer from low compliance rates. Here, we report the identification of three …

… An alternative to this is to complement DNA methylation marker screening with sensitive
imaging techniques to identify the cancer site. Another option is to examine remote media that …

… normally need bisulfide treatment, methylated nucleotide labeling or PCR amplification. …
detection of DNA methylation, assay of DNA methyltransferase (MTase) activity and screening of …

… Our approach turns epigenetic studies into a genomics technology and makes targeted
genome-wide methylation screening possible. In addition to mRNA expression arrays and …

… Prep, Hologic), comparing DNA methylation levels in samples from … test to cervical cancer
screening algorithms worldwide. Our … the use of precision DNA methylation algorithms to triage …

… DNA methylation-driven genes through integrating the transcriptomic as well as DNA methylation
… , we further performed feature selection on DNA methylation-driven genes, designed a …

… Biomarkers are crucial in the screening of patients with a high risk of developing cancer, …
In this review, we summarise current knowledge on methylated DNA and its implications in …