… model (robust regression), which is different from the nonlinear trajectory of cognitive decline
previously proposed in a hypothetical model … recall, Alzheimer Disease Assessment Scale-…

… However, we present this model with some reservations; although DNA methylation and
demethylation have been traditionally associated with transcriptional repression and activation, …

… APP-sw-expressing AD model cell line. To identify genes whose expression was regulated
by DNA methylation status, we performed integrated analysis of CpG methylation and mRNA …

… Although this study was conducted in a stress animal model, it still provides evidence from
an epigenetic perspective for NPAS4 as a possible target. Another molecule involved in tau …

… The “epigenetic clock” is a DNA methylation–based estimate of biological age and is
correlated with chronological age—the greatest risk factor for Alzheimer's disease (AD). Genetic …

… of novel disease-associated genes. This study investigates the genome-wide DNA methylation
… The methylated DNA fragments in the genome of each sample were enriched by MeDIP …

… In particular, DNA methylation dynamics are found to be essential components of epigenetic
… on DNA methylation in neurodegenerative diseases, with a special focus on methylation of 5…

… The study revealed that one half of the loci where DNA methylation and age, which are
associated in a naïve model, can be responsible for the factors affecting demographic features …

… Alzheimer’s disease (AD). In this study we measured genome-wide DNA methylation by
luminometric methylation … of genome-wide DNA methylation, on DNA isolated from peripheral …

… If we consider all 71 CpGs in one comprehensive model, they explained 28.7% of the … in
DNA methylation that we observed most likely represent the altered methylation state of a subset …