[HTML][HTML] Integrated Genome-Wide Analysis of DNA Methylation and Gene Expression in the Hippocampi of 5xFAD Alzheimer's Disease Mouse Model
S Lee, HJ Lee, JM Chun, B Jung, J Kim… - Journal of Integrative …, 2024 - imrpress.com
… , we confirmed the DNA methylation status and mRNA levels … In terms of DNA methylation
status, the methylation of genes, … no significant change in the methylation level of Akap2 was …
status, the methylation of genes, … no significant change in the methylation level of Akap2 was …
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease
… Alzheimer’s disease entorhinal cortex. We demonstrate that previous estimates of DNA
hypermethylation in ANK1 in Alzheimer’s disease … regression models looking for an association …
hypermethylation in ANK1 in Alzheimer’s disease … regression models looking for an association …
Attempt to predict A/T/N-based Alzheimer's disease cerebrospinal fluid biomarkers using a peripheral blood DNA methylation clock
…, Alzheimer's Disease Neuroimaging … - … Alzheimer's disease …, 2020 - content.iospress.com
… blood DNA methylation clock, which reflects the effect of biological aging on DNA methylation
(DNAme) status … a predictive model for each of A/T/N binary statuses in AD patients using …
(DNAme) status … a predictive model for each of A/T/N binary statuses in AD patients using …
Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer's disease
M Konki, M Malonzo, IK Karlsson, N Lindgren… - Clinical …, 2019 - Springer
… for Alzheimer’s disease (AD). The association of the disease status with DNA methylation
was examined with linear mixed effects model including gender, zygosity, age, and interaction …
was examined with linear mixed effects model including gender, zygosity, age, and interaction …
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
… Spnb4 according to DNA methylation microarray values (C) and pyrosequencing (D) in the
frontal cortex of APP-PSEN1 and 3xTg-AD Alzheimer's disease mouse models in relation to …
frontal cortex of APP-PSEN1 and 3xTg-AD Alzheimer's disease mouse models in relation to …
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain
N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… DNA methylation (5-methylcytosine [5mC]) is one of several epigenetic markers altered
in Alzheimer's disease (AD) brain. More recently, attention has been given to DNA …
in Alzheimer's disease (AD) brain. More recently, attention has been given to DNA …
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
G Shireby, EL Dempster, S Policicchio… - Nature …, 2022 - nature.com
… Our initial EWAS model leveraged matched DNA methylation data from both the DLPFC
and OCC for each donor to maximize power to detect cortical DMPs associated with AD …
and OCC for each donor to maximize power to detect cortical DMPs associated with AD …
Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease
R Lardenoije, DLA van den Hove, M Havermans… - Molecular and Cellular …, 2018 - Elsevier
… markers of DNA methylation and hydroxymethylation in a range of animal models of AD,
and their correlations with amyloid plaque load. Three transgenic mouse models, including the …
and their correlations with amyloid plaque load. Three transgenic mouse models, including the …
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1
P Cronin, MJ McCarthy, ASP Lim, DP Salmon… - Alzheimer's & …, 2017 - Elsevier
… clock, and changes in DNA methylation have been reported in … We hypothesized that aberrant
DNA methylation may affect … Our results indicate that cycles of DNA methylation contribute …
DNA methylation may affect … Our results indicate that cycles of DNA methylation contribute …
[HTML][HTML] Association between DNA methylation of the BDNF promoter region and clinical presentation in Alzheimer's disease
T Nagata, N Kobayashi, J Ishii, S Shinagawa… - … cognitive disorders …, 2015 - karger.com
… study, we examined whether DNA methylation of the brain-… Alzheimer's disease (AD).
Methods: Of 20 patients with AD and 20 age-matched normal controls (NCs), the DNA methylation …
Methods: Of 20 patients with AD and 20 age-matched normal controls (NCs), the DNA methylation …